R
Rajesh Kumar
Researcher at Himachal Pradesh University
Publications - 6966
Citations - 180095
Rajesh Kumar is an academic researcher from Himachal Pradesh University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 149, co-authored 4439 publications receiving 140830 citations. Previous affiliations of Rajesh Kumar include Guru Nanak Dev University & Intuitive Surgical.
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Journal ArticleDOI
TERT promoter mutations and telomere length in adult malignant gliomas and recurrences
Barbara Heidenreich,P. Sivaramakrishna Rachakonda,Ismail Hosen,Florian Volz,Kari Hemminki,Astrid Weyerbrock,Rajesh Kumar +6 more
TL;DR: While the data affirm the role of TERT promoter mutations in glial tumors, effects on transcription and telomeres length emphasise the importance of telomere biology in disease genesis and outcome.
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5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes.
Barbara Pardini,Rajesh Kumar,Alessio Naccarati,Jan Novotny,Rashmi B. Prasad,Asta Försti,Asta Försti,Kari Hemminki,Kari Hemminki,Pavel Vodicka,Justo Lorenzo Bermejo,Justo Lorenzo Bermejo +11 more
TL;DR: The role of six genetic variants in the MTHFR and 5-methylenetetrahydrofolate-homocysteine methyltransferase reductase (MTRR) genes on the clinical outcome in 273 colorectal cancer patients who were administered a 5-FU based regimen as first-line post-operative therapy is investigated.
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Mutations in TERT promoter and FGFR3 and telomere length in bladder cancer.
Ismail Hosen,P. Sivaramakrishna Rachakonda,Barbara Heidenreich,Petra J. de Verdier,Charlotta Ryk,Charlotta Ryk,Gunnar Steineck,Gunnar Steineck,Kari Hemminki,Kari Hemminki,Rajesh Kumar +10 more
TL;DR: The finding of shorter telomeres in tumors with TERT promoter and/or FGFR3 mutations than without mutations implies mechanistic relevance of telomere biology in cancer progression and shows that the TERT promoters can potentially be used as markers to refine selection of patients for different treatments.
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Diuretic 18F-FDG PET/CT imaging for detection and locoregional staging of urinary bladder cancer: prospective evaluation of a novel technique.
TL;DR: Diuretic 18F-FDG PET/CT is highly sensitive and specific and plays an important role in improving detection of the primary tumour and locoregional staging of urinary bladder tumours.
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High Diversity of Group A Streptococcal emm Types in an Indian Community: The Need to Tailor Multivalent Vaccines
Nilay Dey,David J. McMillan,Penny Yarwood,Rajan Joshi,Rajesh Kumar,Michael F. Good,Kadaba S. Sriprakash,Harpreet Vohra +7 more
TL;DR: Molecular characterization of isolates recovered from patients in northern India is performed in an attempt to study the circulating M types and their N terminal sequence variability, reporting tremendous diversity in GAS strains recovered from symptomatic patients.