Rajshekhar Karpoormath

Bio: Rajshekhar Karpoormath is an academic researcher from University of KwaZulu-Natal. The author has contributed to research in topics: Chemistry & Combinatorial chemistry. The author has an hindex of 22, co-authored 97 publications receiving 1340 citations. Previous affiliations of Rajshekhar Karpoormath include College of Health Sciences, Bahrain.

Transition-metal-based layered double hydroxides tailored for energy conversion and storage

Abstract: Currently, energy storage devices draw considerable attention owing to the growing need for clean energy. The depletion of fossil fuels and the generation of greenhouse gases have led to the development of alternative, environmentally friendly energy storage devices. Supercapacitors with high power densities are excellent devices for energy storage. Although carbon-based materials are widely used in such devices, their non-faradic behavior in electrical double layer capacitors (EDLCs) limits the maximum power density that can be generated. In contrast, the faradaic mechanism of transition metal hydroxides results in better capacitance rates along with good stability during cycling. This review is confined to nickel cobalt layered double hydroxides (NiCo LDHs) classified based on the fabrication of electrodes for application in supercapacitors. We discuss the growth of the active LDH material in situ or ex situ on the current collector and how the synthesis can affect the crystal structure as well as the electrochemical performance of the electrode.

Metal oxide nanoparticles in electrochemical sensing and biosensing: a review

Abstract: This review (with (318) refs) describes progress made in the design and synthesis of morphologically different metal oxide nanoparticles made from iron, manganese, titanium, copper, zinc, zirconium, cobalt, nickel, tungsten, silver, and vanadium. It also covers respective composites and their function and application in the field of electrochemical and photoelectrochemical sensing of chemical and biochemical species. The proper incorporation of chemical functionalities into these nanomaterials warrants effective detection of target molecules including DNA hybridization and sensing of DNA or the formation of antigen/antibody complexes. Significant data are summarized in tables. The review concludes with a discussion or current challenge and future perspectives.

Nitro-Group-Containing Drugs

Abstract: The nitro group is considered to be a versatile and unique functional group in medicinal chemistry. Despite a long history of use in therapeutics, the nitro group has toxicity issues and is often categorized as a structural alert or a toxicophore, and evidence related to drugs containing nitro groups is rather contradictory. In general, drugs containing nitro groups have been extensively associated with mutagenicity and genotoxicity. In this context, efforts toward the structure–mutagenicity or structure–genotoxicity relationships have been undertaken. The current Perspective covers various aspects of agents that contain nitro groups, their bioreductive activation mechanisms, their toxicities, and approaches to combat their toxicity issues. In addition, recent advances in the field of anticancer, antitubercular and antiparasitic agents containing nitro groups, along with a patent survey on hypoxia-activated prodrugs containing nitro groups, are also covered.