Showing papers by "Rakesh K. Jain published in 1985"
TL;DR: In this article, the role of a soluble surfactant with diffusion-controlled surface transfer onto the surface is analyzed and analytical solutions are obtained for the limiting cases of small and large deformations of the bubbles' caps.
75 citations
47 citations
01 Jan 1985
TL;DR: The modified Sandison type rabbit ear chamber was used to study transport in normal and tumor tissue and tumor (VX2 carcinoma) tissue and fluorescein-isothiocyanate tagged dextran was chosen as a tracer substance.
Abstract: Microvascular permeability of macromolecules in normal and tumor tissues was measured under hyperthermic conditions. Fluorescein-isothiocyanate tagged dextran (150,000 molecular weight) was chosen as a tracer substance. The modified Sandison type rabbit ear chamber was used to study transport in normal (mature granulation) tissue and tumor (VX2 carcinoma) tissue. Hyperthermia (43 degrees C and 50 degrees C for one hour) was induced with a precision thermal water bath attached to the chamber. When heated to 43 degrees C, the normal tissue microvascular permeability increased to 9.4 +/- 7.3 X 10(-8) cm/s, but not statistically different from the control value of 7.3 +/- 3.3 X 10(-8) cm/s. When heated to 50 degrees C, the normal tissue microvascular permeability rose about six-fold to 44.4 +/- 35.3 X 10(-8) cm/s (p less than 0.01). When heated to 43 degrees C, the tumor microvascular permeability increased to 89.4 +/- 29.7 X 10(-8) cm/s, but not statistically different from the control value of 57.3 +/- 39.2 X 10(-8) cm/s. However, when the tumor tissue was heated to 50 degrees C, its permeability nearly doubled to 112.2 +/- 20.8 X 10(-8) cm/s (p less than 0.025).
35 citations
01 Jan 1985
TL;DR: The application of cautery using heated metals or lenses remained popular among the medical community until the middle of the nineteenth century, when more sophisticated methods for elevating local tissue temperatures became available (e.g., diathermy and ultrasound).
Abstract: Heat in various forms has been exploited by mankind for therapeutic purposes since ancient times. The Egyptians (~3000 b.c.) were the first to use cautery against tumors and various nonmalignant diseases(1). The Hindus (~2000 b.c.) used cautery to control surface lesions during the Aryan civilization.(2) The importance of therapeutic application of heat in the Greek civilization is reflected in the preceding aphorism attributed to Hippocrates (460–357 b.c.). He recommended cautery (with a red-hot iron) for small tumors and many other diseases(3–5) The application of cautery using heated metals or lenses remained popular among the medical community until the middle of the nineteenth century, when more sophisticated methods for elevating local tissue temperatures became available (e.g., diathermy and ultrasound).
17 citations
TL;DR: The results suggest a strong dependence of the stability of membrane systems on the interfacial tensions and the thickness of individual membranes and films and rather weak dependence on their viscosities and elasticities.
10 citations
TL;DR: Methyl 6-(ammonium 2-acetamido-2-deoxy-α-d -glucopyranosyl phosphate)-α- d -mannopyranoide was synthesized and identified by 1H-n.m.r. data, acid hydrolysis, and elemental analysis as discussed by the authors.
7 citations
Journal Article•
6 citations
TL;DR: Observation directe de l'etat triplet du compose cite dans le titre par spectroscopie RPE et etude de ses comportements thermiques.
Abstract: Observation directe de l'etat triplet du compose cite dans le titre par spectroscopie RPE et etude de ses comportements thermiques