R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
Papers
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Posted ContentDOI
Comparing Machine Learning Algorithms for Predicting ICU Admission and Mortality in COVID-19
Sonu Subudhi,Ashish Verma,Ankit B. Patel,C. Corey Hardin,Melin J. Khandekar,Hang Lee,Triantafyllos Stylianopoulos,Lance L. Munn,Sayon Dutta,Rakesh K. Jain +9 more
TL;DR: It is shown that ensemble-based models perform better than other model types at predicting both 5-day ICU admission and 28-day mortality from COVID-19, and implementing such models would help in clinical decision-making for future CO VID-19 and other infectious disease outbreaks.
Journal ArticleDOI
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
William L. Hwang,Karthik A. Jagadeesh,Jimmy A. Guo,Hannah I. Hoffman,Payman Yadollahpour,Jason Reeves,Ramkumar Mohan,Eugene Drokhlyansky,Nicholas Van Wittenberghe,Orr Ashenberg,Samouil L. Farhi,Denis Schapiro,Prajan Divakar,Eric M. Miller,Daniel R. Zollinger,George Eng,Jason M. Schenkel,Jennifer Jeeye Su,Carina Shiau,Philip S. Yu,William A. Freed-Pastor,Domenic Abbondanza,Arnav Mehta,Joshua Gould,Conner Lambden,Caroline B. M. Porter,Alexander M. Tsankov,Danielle Dionne,Julia Waldman,Michael S. Cuoco,Lan Nguyen,Toni Delorey,Devan Phillips,Jaimie L. Barth,Marina Kem,Clifton Rodrigues,Debora Ciprani,Jorge Roldan,Piotr Zelga,Vjola Jorgji,Jonathan H. Chen,Zackery A. Ely,Daniel Zhao,Kit Fuhrman,Robin Fropf,Joseph M. Beechem,Jay S. Loeffler,David P. Ryan,Colin D. Weekes,Cristina R. Ferrone,Motaz Qadan,Martin J. Aryee,Rakesh K. Jain,Donna Neuberg,Jennifer Y. Wo,Theodore S. Hong,Ramnik J. Xavier,Andrew J. Aguirre,Orit Rozenblatt-Rosen,Mari Mino-Kenudson,Carlos Fernandez-del Castillo,Andrew S. Liss,David Ring,Tyler Jacks,Aviv Regev +64 more
TL;DR: A high-resolution molecular landscape of the cellular subtypes and spatial communities that compose PDAC is constructed using single-nucleus RNA sequencing and whole-transcriptome digital spatial profiling of 43 primary PDAC tumor specimens that either received neoadjuvant therapy or were treatment naive.
Journal ArticleDOI
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis
Giorgio Seano,Giulia Chiaverina,Paolo Armando Gagliardi,Laura di Blasio,Alberto Puliafito,Claire Bouvard,Roberto Sessa,Guido Tarone,Lydia Sorokin,Dominique Helley,Rakesh K. Jain,Guido Serini,Federico Bussolino,Luca Primo +13 more
TL;DR: Seano et al. as discussed by the authors reported that blood vessel branching during tumour angiogenesis is mediated by the formation of podosome rosettes that depends on VEGF-A and integrin α6β1.
Journal ArticleDOI
Platelet-derived growth factor receptor-β in Gorham’s disease
Jeroen Hagendoorn,Timothy P. Padera,Torunn I. Yock,G. Petur Nielsen,Emmanuelle di Tomaso,Dan G. Duda,Thomas F. DeLaney,Henning A. Gaissert,Jennifer M. Pearce,Andrew E. Rosenberg,Rakesh K. Jain,David H. Ebb +11 more
TL;DR: Gorham's lymphangiomatosis with expression of platelet-derived growth factor receptor-β and elevated circulating Platelet- derived growth factor-BB is diagnosed in a 17-year-old male with no significant medical history.
Patent
Method for locating tumors prior to needle biopsy
TL;DR: In this paper, a method for locating a lesion within a tissue mass, includes steps of measuring a selected parameter at two or more points in at least one path through the tissue mass.