R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
Papers
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Journal Article
Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice.
TL;DR: A database of spontaneous tumors in retired FVB/N breeders is initiated, the histopathologic characteristics of these tumors are analyzed, and novel tumor lines are established in vivo and in vitro for use in this relatively new but widely used mouse strain.
Patent
Novel succinate compounds, compositions and methods of use and preparation
TL;DR: In this paper, a novel hydroxamic acid compounds are disclosed, which inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes, and are useful as antimicrobials and antibiotics.
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Prevention and Treatment of Lymphatic Metastasis by Antilymphangiogenic Therapy
Rakesh K. Jain,Timothy P. Padera +1 more
TL;DR: He et al. as mentioned in this paper used an ectopic (subcutaneous) model of lung cancer and found an association between lymph vessel density (measured as lymphatic vessel endothelial hyaluronan receptor [LYVE]-1-positive structures) and lymph node metastases.
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Glioma Angiogenesis and Perfusion Imaging: Understanding the Relationship between Tumor Blood Volume and Leakiness with Increasing Glioma Grade
Rakesh K. Jain,Brent Griffith,F Alotaibi,David Zagzag,Howard A. Fine,John G. Golfinos,Lonni Schultz +6 more
TL;DR: There is an increase in relative CBV more than permeability surface-area product in lower grade gliomas, whereas in grade III and especially grade IV glioma, permeable surface- area product increases much more thanrelative CBV.
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Chemotaxis of a Ralstonia sp. SJ98 toward co-metabolizable nitroaromatic compounds.
TL;DR: This is the first report showing chemotaxis of a bacterial strain toward co-metabolizable NACs, which do not serve as sole carbon and energy source to strain SJ98 but are partially transformed in the presence of an alternate carbon source such as succinate.