R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Journal ArticleDOI
A convenient synthesis of N-acetyllactosamine-linked oligosaccharides from phenyl 3,6,2′,3′,4′,6′-hexa-O-acetyl- 2-deoxy-2-phthalimido-1-thio-β-lactopyranoside☆
Journal Article
Cell-surface sensors for real-time probing of cellular environments
Weian Zhao,Sebastian Schafer,Jonghoon Choi,Yvonne J. Yamanaka,Maria L. Lombardi,Suman Bose,Alicia L. Carlson,Joseph A. Phillips,Weisuong Teo,Ilia A. Droujinine,Cheryl H. Cui,Rakesh K. Jain,Jan Lammerding,J. Christopher Love,Charles P. Lin,Debanjan Sarkar,Rohit Karnik,Jeffrey M. Karp +17 more
TL;DR: A fluorescent sensor attached to a cell membrane can detect signalling molecules in the cellular environment and can quantitatively detect with high spatial and temporal resolution PDGF that is added in cell culture medium or secreted by neighbouring cells.
Journal ArticleDOI
Characterization of distinct Gal:3-O-sulfotransferase activities in human tumor epithelial cell lines and of calf lymph node GlcNAc : 6-O-sulfotransferase activity.
E. V. Chandrasekaran,Rakesh K. Jain,John Rhodes,Ram Chawda,Conrad F. Piskorz,Khushi L. Matta +5 more
TL;DR: The Group A enzyme activity is present in human breast tumor epithelial cell lines, with some exceptions, and the Gal : 3-O-sulfotransferases show specific binding to Aleuria aurantia lectin, suggesting the presence of asparagine linked carbohydrate chains containing an inner core α1,6-fucosyl residue on these enzymes.
Journal ArticleDOI
Mast Cells Contribute to Radiation-Induced Vascular Hyperpermeability
Kyung Ran Park,Wayne L. Monsky,Chang Geol Lee,Chang Ho Song,Dong Heui Kim,Rakesh K. Jain,Dai Fukumura +6 more
TL;DR: Experimental evidence is provided indicating that mast cells contribute to the increase in vascular permeability for albumin in normal mouse skin after irradiation, and exposure to radiation induces vascular hyperpermeability in a dose-dependent manner.