R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
Papers
More filters
Journal ArticleDOI
Reduction of rigidity in human activated natural killer cells by thioglycollate treatment
Robert J. Melder,Rakesh K. Jain +1 more
TL;DR: It is indicated that short term culture with TGA may be used to significantly reduce NK cell rigidity without decreasing cell viability or function and thioglycollate may be a useful compound for altering the rheological properties of activated lymphocytes prior to adoptive transfer.
Journal ArticleDOI
Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients.
Yves Boucher,Ashwin S. Kumar,Ashwin S. Kumar,Jessica M. Posada,Jessica M. Posada,Evisa Gjini,Evisa Gjini,Kathleen L. Pfaff,Mikel Lipschitz,Ana Lako,Ana Lako,Dan G. Duda,Scott J. Rodig,Scott J. Rodig,F. Stephen Hodi,Rakesh K. Jain +15 more
TL;DR: In this paper, a single dose of bevacizumab reduced the density of angiopoietin-2-positive vessels while improving the infiltration of CD4+ T and CD8+ T cells, and mature dendritic cells in patients with primary triple-negative breast cancer.
Proceedings ArticleDOI
Energy audit of residential buildings to gain energy efficiency credits for LEED certification
Rohit Sharma,Rakesh K. Jain +1 more
TL;DR: In this article, the authors reviewed the initial attempts to understand the energy consumption patterns in a residential building and to reduce the energy consumptions, a case study is included to investigate the reduction in energy consumption per unit in order to make building energy efficient and a feasibility study is done to check the increase in construction cost to gain energy efficiency credits for LEED certification.
Journal ArticleDOI
Novel N-chloroheterocyclic antimicrobials
Charles Francavilla,Eric Douglas Turtle,Bum Tae Kim,Donogh J R O'Mahony,Timothy P. Shiau,Eddy Low,Nichole J Alvarez,Chris Celeri,Louisa D'Lima,Lisa C Friedman,Francis S Ruado,Ping Xu,Meghan Zuck,Mark B. Anderson,Ramin Najafi,Rakesh K. Jain +15 more
TL;DR: Of the compounds examined, the N-chloroamine series were found superior over N- chloroamide series in regards to exhibiting high antimicrobial activity, low cytotoxicity, and long-term aqueous stability.
Journal ArticleDOI
In vivo compression and imaging in mouse brain to measure the effects of solid stress.
Hadi Tavakoli Nia,Hadi Tavakoli Nia,Meenal Datta,Giorgio Seano,Giorgio Seano,Sue Zhang,William Ho,William Ho,Sylvie Roberge,Peigen Huang,Lance L. Munn,Rakesh K. Jain +11 more
TL;DR: An in vivo compression device that simulates the solid mechanical forces exerted by a growing tumor on the surrounding brain tissue and delineates the physical versus biological effects of a tumor is developed.