R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Kinetics of biodegradation of p-nitrophenol by different bacteria.
TL;DR: Three bacterial species, i.e., Ralstonia sp.
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OxDBase: a database of oxygenases involved in biodegradation
TL;DR: Due to the importance of the oxygenases in chemical synthesis of drug intermediates and oxidation of xenobiotic compounds, OxDBase database would be very useful tool in the field of synthetic chemistry as well as bioremediation.
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Cancer cell associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors
Jean Yannis Perentes,Nathaniel D. Kirkpatrick,Satoshi Nagano,Eve Y. Smith,Christine M. Shaver,Dennis C. Sgroi,Igor Garkavtsev,Lance L. Munn,Rakesh K. Jain,Yves Boucher +9 more
TL;DR: It is established that MT1-MMP activity in breast tumors is essential for BVI, but not LVI, and that it should be further explored as a predictor and therapeutic target of hematogenous metastasis in TNBC patients.
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Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks in vivo
Walid S. Kamoun,Sung-Suk Chae,Delphine A. Lacorre,James A. Tyrrell,Mariela Mitre,Marijn A. Gillissen,Dai Fukumura,Rakesh K. Jain +7 more
TL;DR: Using this methodology, it is shown that blood velocity profiles are asymmetric near intussusceptive tissue structures in tumors in mice and that subpopulations of vessels, classified by functional parameters, exist in and around a tumor and in normal brain tissue.
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Endothelial Nitric Oxide Synthase Regulates Microlymphatic Flow via Collecting Lymphatics
Jeroen Hagendoorn,Timothy P. Padera,Satoshi Kashiwagi,Naohide Isaka,Fatima Noda,Michelle I. Lin,Paul L. Huang,William C. Sessa,Dai Fukumura,Rakesh K. Jain +9 more
TL;DR: The results provide the first in vivo evidence that eNOS affects function of the whole microlymphatic system and that it is regulated via the collecting lymphatics.