R
Ralf Lenigk
Researcher at Motorola
Publications - 16
Citations - 1872
Ralf Lenigk is an academic researcher from Motorola. The author has contributed to research in topics: Microfluidics & Biochip. The author has an hindex of 11, co-authored 16 publications receiving 1819 citations. Previous affiliations of Ralf Lenigk include University of Arizona & Arizona State University.
Papers
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Journal ArticleDOI
Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection.
TL;DR: The device provides a cost-effective solution to direct sample-to-answer genetic analysis and thus has a potential impact in the fields of point-of-care genetic analysis, environmental testing, and biological warfare agent detection.
Journal ArticleDOI
Hybridization enhancement using cavitation microstreaming.
TL;DR: A micromixing technique based on cavitation microstreaming principle that was developed to accelerate hybridization process is explained, and it is shown that air bubbles resting on a solid surface and set into vibration by a sound field generated steady circulatory flows, resulting in global convection flows and, thus, rapid mixing.
Journal ArticleDOI
DNA Amplification and Hybridization Assays in Integrated Plastic Monolithic Devices
Yingjie Liu,Cory B. Rauch,Randall L. Stevens,Ralf Lenigk,Jianing Yang,David B. Rhine,Piotr Grodzinski +6 more
TL;DR: Asymmetrical PCR amplification and subsequent hybridization detection of both Escherichia coli K-12 MG1655 and Enterococcus faecalis DNAE genes have been successfully demonstrated in these disposable monolithic devices.
Journal ArticleDOI
Single-use, thermally actuated paraffin valves for microfluidic applications
TL;DR: In this article, a thermally actuated valving concept using paraffin as single-use valving material was developed, which undergoes a phase transition in response to changes in temperature.
Patent
Enhanced mixing in microfluidic devices
TL;DR: In this paper, the volume of a gas pocket within a microfluidic device is changed to enhance mixing and hybridization kinetics, which can result in enhanced mixing and reaction kinetics.