R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Multiplicity Considerations in Clinical Trials.
TL;DR: Addressing Multiple Comparisons in Clinical Trials Making multiple comparisons increases the likelihood that a chance association could be interpreted as causal and a number of statistical approaches are considered.
Journal ArticleDOI
Serum γ-Glutamyl Transferase and Risk of Heart Failure in the Community
Ravi Dhingra,Philimon Gona,Thomas J. Wang,Thomas J. Wang,Caroline S. Fox,Ralph B. D'Agostino,Ralph B. D'Agostino,Ramachandran S. Vasan,Ramachandran S. Vasan +8 more
TL;DR: Higher serum GGT concentrations within the “normal” range were associated with greater risk of heart failure and incrementally improved prediction of heart fail risk, in this prospective study of a large community-based sample.
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Treatment of Insomnia in Depressed Insomniacs: Effects on Health-related Quality of Life, Objective and Self-Reported Sleep, and Depression
W. Vaughn McCall,Jill N. Blocker,Ralph B. D'Agostino,James Kimball,Niki Boggs,Barbara Lasater,Roger F. Haskett,Andrew D. Krystal,William M. McDonald,Peter B. Rosenquist +9 more
TL;DR: ESZ treatment of insomnia in depressed patients is associated with multiple favorable outcomes, including superior improvement in HRQOL, depression severity, and sleep.
Journal ArticleDOI
Lung tumor promotion by curcumin
Stephanie T. Dance-Barnes,Nancy D. Kock,Joseph E. Moore,Elaine Y. Lin,Libyadda J. Mosley,Ralph B. D'Agostino,Thomas P. McCoy,Alan J. Townsend,Mark Steven Miller +8 more
TL;DR: The results suggest that curcumin may exhibit organ-specific effects to enhance reactive oxygen species formation in the damaged lung epithelium of smokers and ex-smokers in chemopreventive trials ofCurcumin.
Journal ArticleDOI
Survival and Functional Status 20 or More Years After First Stroke The Framingham Study
Glen E. Gresham,Margaret Kelly-Hayes,Philip A. Wolf,Alexa S. Beiser,Carlos S. Kase,Ralph B. D'Agostino +5 more
TL;DR: In the Framingham cohort, 20-plus-year stroke survivors showed greater mortality than age- and sex-matched control subjects; functionally, however, the groups were very similar and in general quite independent.