R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study
Ravi V. Shah,Ashish Yeri,Venkatesh L. Murthy,Joseph M. Massaro,Ralph B. D'Agostino,Jane E. Freedman,Michelle T. Long,Caroline S. Fox,Saumya Das,Emelia J. Benjamin,Ramachandran S. Vasan,Christopher J. O'Donnell,Udo Hoffmann +12 more
TL;DR: This proof-of-concept analysis demonstrates that unsupervised machine learning, in an asymptomatic community cohort, identifies an unfavorable multiorgan phenotype associated with adverse health outcomes, especially in elderly American adults.
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Physical Activity, Insulin Sensitivity, and Hypertension among US Adults: Findings from the Insulin Resistance Atherosclerosis Study
Capri G. Foy,Kristie L. Foley,Ralph B. D'Agostino,David C. Goff,Elizabeth J. Mayer-Davis,Lynne E. Wagenknecht +5 more
TL;DR: The results suggest that longitudinal studies are warranted to determine whether insulin sensitivity is a mediator of the relation between physical activity and hypertension.
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Guideline-Based Statin Eligibility, Cancer Events, and Noncardiovascular Mortality in the Framingham Heart Study.
TL;DR: Recommendation-based statin eligibility accurately identified patients at a higher risk of developing cancer and cancer-related mortality and shared risk profiles and potential benefits of statins between cancer and cardiovascular outcomes may provide a unique opportunity to improve population health.
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Correlates of Dietary Intake in Youth with Diabetes: Results from the SEARCH for Diabetes in Youth Study
Andrey V. Bortsov,Angela D. Liese,Ronny A. Bell,Dana Dabelea,Ralph B. D'Agostino,Richard F. Hamman,Georgeanna J. Klingensmith,Georgeanna J. Klingensmith,Jean M. Lawrence,David M. Maahs,David M. Maahs,Robert E. McKeown,Santica M. Marcovina,Joan Thomas,Elizabeth J. Mayer-Davis,Elizabeth J. Mayer-Davis +15 more
TL;DR: Identified demographic and behavioral correlates may help dietitians to focus on groups of youth with diabetes who have lower adherence to a healthful diet and Diet counseling groups may be tailored according to these major determinants.
Journal ArticleDOI
Variation in susceptibility of human malignant melanomas to oncolytic vesicular stomatitis virus.
Aaron U. Blackham,Scott A. Northrup,Mark C. Willingham,Ralph B. D'Agostino,Douglas S. Lyles,John H. Stewart +5 more
TL;DR: M51R-VSV is a viable anti-cancer therapy, but susceptibility varies among melanomas, and specific mechanisms of resistance will be exploited to expand the therapeutic efficacy of M51R -VSV.