scispace - formally typeset
R

Ralph B. D'Agostino

Researcher at Wake Forest University

Publications -  1336
Citations -  250792

Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.

Papers
More filters
Journal ArticleDOI

Global Two-Group Multiple Endpoint Adjustment Methods Applied to Clinical Trials

TL;DR: In this article, the authors discuss some of these global multiple endpoint adjustment methods in the context of clinical trial applications where two treatments are being compared (for example, active treatment with a placebo), and give some simulation results to assess their performance regarding the a-level protection and power.
Journal ArticleDOI

The Prognostic and Therapeutic Value of the Mutational Profile of Blood and Tumor Tissue in Head and Neck Squamous Cell Carcinoma.

TL;DR: This study illustrates the circulating and tumor genomic profile in the largest HNSCC cohort to date, underscoring the potential utility of ctDNA in prognostication and precision oncology treatment and reports for the first time the prognostic value of cTDNA sequencing.
Journal ArticleDOI

Frequency of Transition From Stage A to Stage B Heart Failure After Initiating Potentially Cardiotoxic Chemotherapy

TL;DR: To determine the prevalence of American Heart Association/American College of Cardiology Foundation (AHA/ACCF) heart failure (HF) stages after potentially cardiotoxic chemotherapy was initiated, 143 Stage A HF patients with breast cancer, lymphoma and leukemia, renal cell carcinoma, or sarcoma were surveyed.
Journal ArticleDOI

Absence of Association Between Polymorphisms in the Hemostatic Factor Pathway Genes and Carotid Intimal Medial Thickness The Framingham Heart Study

TL;DR: There is no evidence for an association between well-studied polymorphisms in the hemostatic factor genes and carotid IMT, a heritable, quantitative measure of atherosclerosis that is predictive of subsequent myocardial infarction and stroke.