R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor
Jaclyn J. Renfrow,Jaclyn J. Renfrow,Michael H. Soike,James L. West,Shakti H. Ramkissoon,Shakti H. Ramkissoon,Linda J. Metheny-Barlow,Linda J. Metheny-Barlow,Ryan T. Mott,Ryan T. Mott,Carol Kittel,Ralph B. D'Agostino,Ralph B. D'Agostino,Stephen B. Tatter,Stephen B. Tatter,Adrian W. Laxton,Adrian W. Laxton,Mark B. Frenkel,Gregory A. Hawkins,Denise Herpai,Denise Herpai,Stephanie Sanders,Stephanie Sanders,Jann N. Sarkaria,Glenn J. Lesser,Glenn J. Lesser,Waldemar Debinski,Waldemar Debinski,Roy E. Strowd,Roy E. Strowd +29 more
TL;DR: It is concluded that HIF2α is a reasonable novel therapeutic target as expressed in the majority of glioblastomas in the authors' cohort, andPT2385 as a single-agent was efficacious in vivo, however, an increase in animal survival was not seen with PT2385 in combination with RT/TMZ.
Journal ArticleDOI
Cigarette smoking and cardio-renal events in patients with atherosclerotic renal artery stenosis.
Christopher A. Drummond,Pamela S. Brewster,Wencan He,Kaili Ren,Yanmei Xie,Katherine R. Tuttle,Steven T. Haller,Kenneth Jamerson,Lance D. Dworkin,Donald E. Cutlip,Timothy P. Murphy,Ralph B. D'Agostino,William L. Henrich,Jiang Tian,Joseph I. Shapiro,Christopher J. Cooper +15 more
TL;DR: It is concluded that smoking has a significant association with deleterious cardio-renal outcomes in patients with renovascular hypertension.
Journal ArticleDOI
Nasal carriage of Staphylococcus aureus among patients receiving allergen-injection immunotherapy: associated factors and quantitative nasal cultures.
TL;DR: Patients undergoing desensitization have a higher nasal carriage rate of S aureus, however, factors other than the regular use of needles, and in particular abnormalities related to the atopic constitution of these patients, may predispose this population for S aures carriage.
Journal ArticleDOI
A technique for summarizing longitudinal data
TL;DR: This work proposes a technique for reducing a set of longitudinal data into four common summary statistics together with time, and derives them mathematically, thus justifying their use, which simplifies the subsequent analyses, and improves the interpretation of the results.
Journal ArticleDOI
Quantifying Cardiometabolic Risk Using Modifiable Non–Self-Reported Risk Factors
Miguel Marino,Yi Li,Michael J. Pencina,Ralph B. D'Agostino,Lisa F. Berkman,Orfeu M. Buxton,Orfeu M. Buxton +6 more
TL;DR: This study presents a risk factor algorithm that provides a convenient and informative way to quantify cardiometabolic risk on the basis of modifiable risk factors that can motivate an individual's commitment to prevention and intervention.