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Ralph B. D'Agostino

Researcher at Wake Forest University

Publications -  1336
Citations -  250792

Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.

Papers
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Book ChapterDOI

Evaluation of the Performance of Survival Analysis Models: Discrimination and Calibration Measures

Ralph B. D'Agostino, +1 more
- 01 Jan 2003 - 
TL;DR: This chapter focuses on the evaluation of the performance of an HRAF with regard to its ability to predict the outcome variable and considers a time to event survival model with censored observations, such as the Cox regression model.
Journal ArticleDOI

Precursors of extracranial carotid atherosclerosis in the Framingham Study.

J. S. Fine-Edelstein, +6 more
- 01 Jun 1994 - 
TL;DR: The results indicate that both current and former smoking in both sexes was related to the degree of carotid atherosclerosis, and a multivariate logistic regression model showed that age, cigarette smoking, systolic blood pressure, and cholesterol were independently related to carotids.
Journal ArticleDOI

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis.

Eliano Pio Navarese, +14 more
- 07 Jul 2015 - 
TL;DR: In this paper, the efficacy and safety of PCSK9 antibodies in adults with hypercholesterolemia were evaluated in a randomized, controlled trial (RCT) and the primary end points were all-cause and cardiovascular mortality.
Journal ArticleDOI

Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study.

Rhoda Au, +7 more
- 01 Feb 2006 - 
TL;DR: In this younger community-based population of nondemented individuals, those with large WMH volume, as compared with those with less or no WMH volumes, performed significantly worse in cognitive domains generally associated with frontal lobe systems and, to a lesser extent, the medial temporal area.
Journal ArticleDOI

Fasting Plasma Homocysteine Levels in the Insulin Resistance Syndrome: The Framingham Offspring Study

James B. Meigs, +7 more
- 01 Aug 2001 - 
TL;DR: Hyperhomocysteinemia and abnormal urinary albumin excretion are both associated with hyperinsulinemia and may partially account for increased risk of CVD associated with insulin resistance, and support the hypothesis that endothelial dysfunction is associated with expression of the IRS.