R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Sex and Age Differences in Lipoprotein Subclasses Measured by Nuclear Magnetic Resonance Spectroscopy: The Framingham Study
David S. Freedman,James D. Otvos,Elias J. Jeyarajah,Irina Shalaurova,L. Adrienne Cupples,Helen Parise,Ralph B. D'Agostino,Peter W.F. Wilson,Ernst J. Schaefer +8 more
TL;DR: Women have a less atherogenic subclass profile than men, even after accounting for differences in lipid concentrations, and women also had a lower-risk subclass profile consisting of larger LDL and HDL particles than men.
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Gender and C-reactive protein: data from the Multiethnic Study of Atherosclerosis (MESA) cohort.
Susan G. Lakoski,Mary Cushman,Michael H. Criqui,Tatjana Rundek,Roger S. Blumenthal,Ralph B. D'Agostino,David M. Herrington +6 more
TL;DR: Evaluation of gender-specific CRP cut points to determine cardiovascular risk should be considered and this pattern of higher CRP levels in women was consistent across all ethnic subgroups even after multivariable adjustment.
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Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease
Ann Marie Navar-Boggan,Eric D. Peterson,Ralph B. D'Agostino,Benjamin Neely,Allan D. Sniderman,Michael J. Pencina +5 more
TL;DR: Cumulative exposure to hyperlipidemia in young adulthood increases the subsequent risk of CHD in a dose-dependent fashion and adults with prolonged exposure to even moderate elevations in non–high-density lipoprotein cholesterol have elevated risk for future CHD and may benefit from more aggressive primary prevention.
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Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham Study.
Luc Djoussé,Daniel Levy,Emelia J. Benjamin,Susan J. Blease,Ana L. Russ,Martin G. Larson,Joseph M. Massaro,Ralph B. D'Agostino,Philip A. Wolf,R. Curtis Ellison +9 more
TL;DR: The data indicate little association between long-term moderate alcohol consumption and the risk of AF, but a significantly increased risk ofAF among subjects consuming >36 g/day (approximatively >3 drinks/day).
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Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans.
David H. McDermott,Alan M. Fong,Qiong Yang,Joan M.G. Sechler,L. Adrienne Cupples,Maya N. Merrell,Peter W.F. Wilson,Ralph B. D'Agostino,Christopher J. O'Donnell,Dhavalkumar D. Patel,Philip M. Murphy +10 more
TL;DR: In this article, the authors showed that FKN-dependent cell-cell adhesion under conditions of physiologic shear is severely reduced in cells expressing CX3CR1-M280.