R
Ramachandran S. Vasan
Researcher at Boston University
Publications - 1214
Citations - 160449
Ramachandran S. Vasan is an academic researcher from Boston University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 172, co-authored 1100 publications receiving 138108 citations. Previous affiliations of Ramachandran S. Vasan include University Health Network & Swinburne University of Technology.
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Journal ArticleDOI
General Cardiovascular Risk Profile for Use in Primary Care The Framingham Heart Study
Ralph B. D'Agostino,Ramachandran S. Vasan,Michael J. Pencina,Philip A. Wolf,Mark R. Cobain,Joseph M. Massaro,William B. Kannel +6 more
TL;DR: A sex-specific multivariable risk factor algorithm can be conveniently used to assess general CVD risk and risk of individual CVD events (coronary, cerebrovascular, and peripheral arterial disease and heart failure) and can be used to quantify risk and to guide preventive care.
Journal ArticleDOI
Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond
TL;DR: Two new measures, one based on integrated sensitivity and specificity and the other on reclassification tables, are introduced that offer incremental information over the AUC and are proposed to be considered in addition to the A UC when assessing the performance of newer biomarkers.
Journal ArticleDOI
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.
Caroline S. Fox,Joseph M. Massaro,Udo Hoffmann,Karla M. Pou,Pál Maurovich-Horvat,Chunyu Liu,Ramachandran S. Vasan,Joanne M. Murabito,James B. Meigs,L. Adrienne Cupples,Ralph B. D'Agostino,Christopher J. O'Donnell +11 more
TL;DR: These findings are consistent with the hypothesized role of visceral fat as a unique, pathogenic fat depot and Measurement of VAT may provide a more complete understanding of metabolic risk associated with variation in fat distribution.
Journal ArticleDOI
Obesity and the Risk of Heart Failure
Satish Kenchaiah,Jane C. Evans,Daniel Levy,Peter W.F. Wilson,Emelia J. Benjamin,Martin G. Larson,William B. Kannel,Ramachandran S. Vasan +7 more
TL;DR: There was an increase in the risk of heart failure of 5 percent for men and 7 percent for women for each increment of 1 in body-mass index after adjustment for established risk factors.
Journal ArticleDOI
Metabolite profiles and the risk of developing diabetes
Thomas J. Wang,Martin G. Larson,Martin G. Larson,Ramachandran S. Vasan,Ramachandran S. Vasan,Susan Cheng,Susan Cheng,Susan Cheng,Eugene P. Rhee,Eugene P. Rhee,Elizabeth L. McCabe,Elizabeth L. McCabe,Gregory D. Lewis,Gregory D. Lewis,Caroline S. Fox,Caroline S. Fox,Paul F. Jacques,Céline Fernandez,Christopher J. O'Donnell,Christopher J. O'Donnell,Christopher J. O'Donnell,Stephen A Carr,Vamsi K. Mootha,Vamsi K. Mootha,Jose C. Florez,Jose C. Florez,Amanda Souza,Olle Melander,Clary B. Clish,Robert E. Gerszten,Robert E. Gerszten +30 more
TL;DR: Findings underscore the potential key role of amino acid metabolism early in the pathogenesis of diabetes and suggest that amino acid profiles could aid in diabetes risk assessment.