R
Raúl González-Domínguez
Researcher at Carlos III Health Institute
Publications - 104
Citations - 2722
Raúl González-Domínguez is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Metabolomics & Medicine. The author has an hindex of 23, co-authored 82 publications receiving 1731 citations. Previous affiliations of Raúl González-Domínguez include University of Huelva & University of Barcelona.
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Journal ArticleDOI
Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies
Marynka Ulaszewska,Christoph H. Weinert,Alessia Trimigno,Reto Portmann,Cristina Andres Lacueva,René Badertscher,Lorraine Brennan,Carl Brunius,Achim Bub,Francesco Capozzi,Marta Cialiè Rosso,Chiara Cordero,Hannelore Daniel,Stéphanie Durand,Bjoern Egert,Paola G. Ferrario,Edith J. M. Feskens,Pietro Franceschi,Mar Garcia-Aloy,Franck Giacomoni,Pieter Giesbertz,Raúl González-Domínguez,Kati Hanhineva,Lieselot Hemeryck,Joachim Kopka,Sabine E. Kulling,Rafael Llorach,Claudine Manach,Fulvio Mattivi,Carole Migné,Linda H. Münger,Beate Ott,Gianfranco Picone,Grégory Pimentel,Estelle Pujos-Guillot,Samantha Riccadonna,Manuela J. Rist,Caroline Rombouts,Josep Rubert,Thomas Skurk,Pedapati S. C. Sri Harsha,Lieven Van Meulebroek,Lynn Vanhaecke,Rosa Vázquez-Fresno,David S. Wishart,Guy Vergères +45 more
TL;DR: A methodological description of nutritional metabolomics is provided that reflects on the state-of-the-art techniques used in the laboratories of the Food Biomarker Alliance as well as points of reflections to harmonize this field.
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Metabolite profiling for the identification of altered metabolic pathways in Alzheimer's disease
TL;DR: Altered levels of metabolites detected in serum between Alzheimer's disease patients and healthy controls confirmed the involvement of multiple affected pathways, such as energy deficiencies, oxidative stress, hyperammonemia, and others.
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Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease
TL;DR: This work represents the first comprehensive characterization of serum phospholipids alterations in relation to Alzheimer's disease, by combining shotgun metabolomics and phospholIPids profiling through different analytical approaches.
Journal ArticleDOI
Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis–mass spectrometry
Raúl González-Domínguez,Antonia García,Tamara García-Barrera,Coral Barbas,José Luis Gómez-Ariza +4 more
TL;DR: A metabolomic approach based on ultrafiltration and analysis by CE‐MS has been used to obtain representative fingerprints of polar metabolites from serum samples in order to distinguish between patients with Alzheimer's disease, mild cognitive impairment, and healthy controls.
Journal ArticleDOI
Metabolomic study of lipids in serum for biomarker discovery in Alzheimer's disease using direct infusion mass spectrometry.
TL;DR: The potential of direct infusion mass spectrometry for the lipidomic characterization of Alzheimer's disease is demonstrated and important metabolic pathways involved in neurodegeneration could be studied on the basis of these perturbations.