R
Ray White
Researcher at University of Utah
Publications - Â 177
Citations - Â 35454
Ray White is an academic researcher from University of Utah. The author has contributed to research in topics: Genetic linkage & Gene. The author has an hindex of 72, co-authored 176 publications receiving 34622 citations. Previous affiliations of Ray White include Huntsman Cancer Institute & Howard Hughes Medical Institute.
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Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
TL;DR: A new basis for the construction of a genetic linkage map of the human genome is described, to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms, when hybridized to restriction digests of an individual's DNA.
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Identification and characterization of the familial adenomatous polyposis coli gene
Joanna Groden,Andrew Thliveris,Andrew Thliveris,Wade S. Samowitz,M. Carlson,Lawrence Gelbert,Lawrence Gelbert,Hans Albertsen,Geoff Joslyn,Geoff Joslyn,Jeff Stevens,Jeff Stevens,Lisa Spirio,Margaret Robertson,Margaret Robertson,Leslie Sargeant,Leslie Sargeant,Karen Krapcho,Karen Krapcho,E. Wolff,E. Wolff,Randall W. Burt,John P. Hughes,Janet A. Warrington,John Douglas Mcpherson,John J. Wasmuth,Denis Le Paslier,Hadi Abderrahim,Daniel Cohen,Mark Leppert,Mark Leppert,Ray White,Ray White +32 more
TL;DR: DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes located within a 100 kb region deleted in two of the patients, and data have established that DP2.5 is the APC gene.
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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
Suzanne J. Baker,Eric R. Fearon,Janice M. Nigro,Stanley R. Hamilton,Ann C. Preisinger,J. Milburn Jessup,P vanTuinen,David H. Ledbetter,David F. Barker,Yusuke Nakamura,Ray White,Bert Vogelstein +11 more
TL;DR: The data suggest that p53 gene mutations may be involved in colorectal neoplasia, perhaps through inactivation of a tumor suppressor function of the wild-type p53 genes.
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Variable number of tandem repeat (VNTR) markers for human gene mapping
Yusuke Nakamura,Mark Leppert,Peter O'Connell,Roger K. Wolff,Tom Holm,Melanie Culver,Cindy Martin,Esther Fujimoto,Mark Hoff,Erika Kumlin,Ray White +10 more
TL;DR: Ten oligomeric sequences derived from the tandem repeat regions of the myoglobin gene, the zeta-globin pseudogene, the insulin gene, and the X-gene region of hepatitis B virus were used to develop a series of single-copy probes that revealed new, highly polymorphic genetic loci whose allele sizes reflected variation in the number of tandem repeats.
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Allelotype of colorectal carcinomas
Bert Vogelstein,Eric R. Fearon,Scott E. Kern,Stanley R. Hamilton,Ann C. Preisinger,Yusuke Nakamura,Ray White +6 more
TL;DR: In addition to its implications concerning the genetic events underlying tumorigenesis, tumor allelotype may provide a molecular tool for improved estimation of prognosis in patients with colorectal cancer.