R
Rebecca C Richmond
Researcher at University of Bristol
Publications - 149
Citations - 7818
Rebecca C Richmond is an academic researcher from University of Bristol. The author has contributed to research in topics: Mendelian randomization & DNA methylation. The author has an hindex of 32, co-authored 132 publications receiving 5038 citations. Previous affiliations of Rebecca C Richmond include Erasmus University Rotterdam & Medical Research Council.
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Journal ArticleDOI
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
Simone Wahl,Alexander W. Drong,Benjamin Lehne,Marie Loh,Marie Loh,Marie Loh,William R. Scott,William R. Scott,Sonja Kunze,Pei-Chien Tsai,Janina S. Ried,Weihua Zhang,Weihua Zhang,Youwen Yang,Sili Tan,Giovanni Fiorito,Lude Franke,Simonetta Guarrera,Silva Kasela,Jennifer Kriebel,Rebecca C Richmond,Marco Adamo,Uzma Afzal,Uzma Afzal,Mika Ala-Korpela,Mika Ala-Korpela,Mika Ala-Korpela,Benedetta Albetti,Ole Ammerpohl,Jane F. Apperley,Marian Beekman,Pier Alberto Bertazzi,S. Lucas Black,Christine Blancher,Marc Jan Bonder,Mario Brosch,Maren Carstensen-Kirberg,Anton J. M. de Craen,Simon de Lusignan,Abbas Dehghan,Mohamed Elkalaawy,Krista Fischer,Oscar H. Franco,Tom R. Gaunt,Jochen Hampe,Majid Hashemi,Aaron Isaacs,Andrew Jenkinson,Sujeet Jha,Norihiro Kato,Vittorio Krogh,Michael Laffan,Christa Meisinger,Thomas Meitinger,Zuan Yu Mok,Valeria Motta,Hong Kiat Ng,Zacharoula Nikolakopoulou,Georgios Nteliopoulos,Salvatore Panico,Natalia Pervjakova,Holger Prokisch,Wolfgang Rathmann,Michael Roden,Federica Rota,Michelle Ann Rozario,Johanna K. Sandling,Johanna K. Sandling,Clemens Schafmayer,Katharina Schramm,Reiner Siebert,Reiner Siebert,P. Eline Slagboom,Pasi Soininen,Pasi Soininen,Lisette Stolk,Konstantin Strauch,E-Shyong Tai,Letizia Tarantini,Barbara Thorand,Ettje F. Tigchelaar,Rosario Tumino,André G. Uitterlinden,Cornelia M. van Duijn,Joyce B. J. van Meurs,Paolo Vineis,Ananda R. Wickremasinghe,Cisca Wijmenga,Tsun-Po Yang,Wei Yuan,Wei Yuan,Alexandra Zhernakova,Rachel L. Batterham,George Davey Smith,Panos Deloukas,Panos Deloukas,Panos Deloukas,Bastiaan T. Heijmans,Christian Herder,Albert Hofman,Cecilia M. Lindgren,Cecilia M. Lindgren,Lili Milani,Pim van der Harst,Annette Peters,Thomas Illig,Caroline L Relton,Melanie Waldenberger,Marjo-Riitta Järvelin,Valentina Bollati,Richie Soong,Tim D. Spector,James Scott,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Paul Elliott,Paul Elliott,Jordana T. Bell,Giuseppe Matullo,Christian Gieger,Jaspal S. Kooner,Harald Grallert,John C. Chambers +123 more
TL;DR: In this article, the authors used epigenome-wide association to show that body mass index (BMI), a key measure of adiposity, is associated with widespread changes in DNA methylation.
Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.
John C. Chambers,Marie Loh,Marie Loh,Marie Loh,Benjamin Lehne,Alexander W. Drong,Jennifer Kriebel,Valeria Motta,Simone Wahl,Hannah R Elliott,Hannah R Elliott,Federica Rota,William R. Scott,William R. Scott,Weihua Zhang,Weihua Zhang,Sian-Tsung Tan,Sian-Tsung Tan,Gianluca Campanella,Marc Chadeau-Hyam,Loic Yengo,Loic Yengo,Rebecca C Richmond,Martyna Adamowicz-Brice,Uzma Afzal,Uzma Afzal,Kiymet Bozaoglu,Zuan Yu Mok,Hong Kiat Ng,François Pattou,François Pattou,Holger Prokisch,Michelle Ann Rozario,Letizia Tarantini,James Abbott,Mika Ala-Korpela,Benedetta Albetti,Ole Ammerpohl,Pier Alberto Bertazzi,Christine Blancher,R. Caiazzo,R. Caiazzo,John Danesh,Tom R. Gaunt,Simon de Lusignan,Christian Gieger,Thomas Illig,Sujeet Jha,Simon Jones,Jeremy B. M. Jowett,Antti J. Kangas,Anuradhani Kasturiratne,Norihiro Kato,Navaratnam Kotea,Sudhir Kowlessur,Janne Pitkäniemi,Prakash P Punjabi,Danish Saleheen,Danish Saleheen,Clemens Schafmayer,Pasi Soininen,Pasi Soininen,E-Shyong Tai,Barbara Thorand,Jaakko Tuomilehto,Ananda R. Wickremasinghe,Soterios A. Kyrtopoulos,Timothy J. Aitman,Christian Herder,Jochen Hampe,Stéphane Cauchi,Stéphane Cauchi,Caroline L Relton,Philippe Froguel,Richie Soong,Paolo Vineis,Marjo-Riitta Järvelin,James Scott,Harald Grallert,Valentina Bollati,Paul Elliott,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Jaspal S. Kooner +84 more
TL;DR: A nested case-control study of DNA methylation in Indian Asians and Europeans with incident type 2 diabetes who were identified from the 8-year follow-up of 25 372 participants in the London Life Sciences Prospective Population study.
Journal ArticleDOI
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Nicole M. Warrington,Robin N Beaumont,Momoko Horikoshi,Felix R. Day,Øyvind Helgeland,Øyvind Helgeland,Øyvind Helgeland,Charles Laurin,Jonas Bacelis,Shouneng Peng,Ke Hao,Bjarke Feenstra,Andrew R. Wood,Anubha Mahajan,Jessica Tyrrell,Jessica Tyrrell,Neil Robertson,N. William Rayner,N. William Rayner,Zhen Qiao,Gunn-Helen Moen,Gunn-Helen Moen,Marc Vaudel,Carmen J. Marsit,Jia Chen,Michael Nodzenski,Theresia M. Schnurr,Mohammad Hadi Zafarmand,Jonathan P. Bradfield,Niels Grarup,Marjolein N. Kooijman,Ruifang Li-Gao,Frank Geller,Tarunveer S. Ahluwalia,Lavinia Paternoster,Rico Rueedi,Rico Rueedi,Ville Huikari,Jouke-Jan Hottenga,Leo-Pekka Lyytikäinen,Alana Cavadino,Alana Cavadino,Sarah Metrustry,Diana L. Cousminer,Diana L. Cousminer,Ying Wu,Elisabeth Thiering,Carol A. Wang,Christian Theil Have,Natalia Vilor-Tejedor,Peter K. Joshi,Jodie N. Painter,Ioanna Ntalla,Ronny Myhre,Niina Pitkänen,Elisabeth M. van Leeuwen,Raimo Joro,Vasiliki Lagou,Vasiliki Lagou,Rebecca C Richmond,Ana Espinosa,Sheila J. Barton,Hazel Inskip,Hazel Inskip,John W. Holloway,Loreto Santa-Marina,Xavier Estivill,Wei Ang,Julie A. Marsh,Christoph Reichetzeder,Letizia Marullo,Berthold Hocher,Kathryn L. Lunetta,Joanne M. Murabito,Caroline L Relton,Manolis Kogevinas,Leda Chatzi,Catherine Allard,Luigi Bouchard,Luigi Bouchard,Marie-France Hivert,Marie-France Hivert,Ge Zhang,Ge Zhang,Louis J. Muglia,Louis J. Muglia,Jani Heikkinen,Camilla Schmidt Morgen,Antoine H. C. van Kampen,Antoine H. C. van Kampen,Barbera D. C. van Schaik,Frank D. Mentch,Claudia Langenberg,Jian'an Luan,Robert A. Scott,Jing Hua Zhao,Gibran Hemani,Susan M. Ring,Amanda J. Bennett,Kyle J. Gaulton,Kyle J. Gaulton,Juan Fernández-Tajes,Natalie R. van Zuydam,Carolina Medina-Gomez,Hugoline G. de Haan,Frits R. Rosendaal,Zoltán Kutalik,Zoltán Kutalik,Pedro Marques-Vidal,Shikta Das,Gonneke Willemsen,Hamdi Mbarek,Martina Müller-Nurasyid,Marie Standl,Emil V. R. Appel,Cilius Esmann Fonvig,Cæcilie Trier,Catharina E. M. van Beijsterveldt,Mario Murcia,Mariona Bustamante,Sílvia Bonàs-Guarch,David M. Hougaard,Josep M. Mercader,Josep M. Mercader,Josep M. Mercader,Allan Linneberg,Katharina E. Schraut,Penelope A. Lind,Sarah E. Medland,Beverley M. Shields,Bridget A. Knight,Jin-Fang Chai,Kalliope Panoutsopoulou,Meike Bartels,Friman Sánchez,Jakob Stokholm,David Torrents,David Torrents,Rebecca K. Vinding,Sara M. Willems,Mustafa Atalay,Bo L. Chawes,Peter Kovacs,Inga Prokopenko,Inga Prokopenko,Marcus A. Tuke,Hanieh Yaghootkar,Katherine S. Ruth,Samuel E. Jones,Po-Ru Loh,Po-Ru Loh,Anna Murray,Michael N. Weedon,Anke Tönjes,Michael Stumvoll,Kim F. Michaelsen,Aino-Maija Eloranta,Timo A. Lakka,Cornelia M. van Duijn,Wieland Kiess,Antje Körner,Harri Niinikoski,Harri Niinikoski,Katja Pahkala,Olli T. Raitakari,Olli T. Raitakari,Bo Jacobsson,Bo Jacobsson,Eleftheria Zeggini,George Dedoussis,Yik Ying Teo,Seang-Mei Saw,Grant W. Montgomery,Harry Campbell,James F. Wilson,Tanja G. M. Vrijkotte,Martine Vrijheid,Eco J. C. de Geus,M. Geoffrey Hayes,Haja N. Kadarmideen,Jens-Christian Holm,Lawrence J. Beilin,Craig E. Pennell,Joachim Heinrich,Linda S. Adair,Judith B. Borja,Karen L. Mohlke,Johan G. Eriksson,Johan G. Eriksson,Elisabeth Widen,Andrew T. Hattersley,Andrew T. Hattersley,Tim D. Spector,Mika Kähönen,Jorma Viikari,Jorma Viikari,Terho Lehtimäki,Dorret I. Boomsma,Sylvain Sebert,Peter Vollenweider,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Hans Bisgaard,Klaus Bønnelykke,Jeff Murray,Mads Melbye,Ellen A. Nohr,Dennis O. Mook-Kanamori,Fernando Rivadeneira,Albert Hofman,Janine F. Felix,Vincent W. V. Jaddoe,Torben Hansen,Charlotta Pisinger,Allan Vaag,Oluf Pedersen,André G. Uitterlinden,Marjo-Riitta Järvelin,Christine Power,Elina Hyppönen,Elina Hyppönen,Denise M. Scholtens,William L. Lowe,George Davey Smith,Nicholas J. Timpson,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Nicholas J. Wareham,Hakon Hakonarson,Hakon Hakonarson,Struan F.A. Grant,Timothy M. Frayling,Debbie A Lawlor,Pål R. Njølstad,Pål R. Njølstad,Stefan Johansson,Stefan Johansson,Ken K. Ong,Mark I. McCarthy,Mark I. McCarthy,John R. B. Perry,David M. Evans,David M. Evans,Rachel M. Freathy,Rachel M. Freathy +245 more
TL;DR: An expanded GWAS of birth weight and subsequent analysis using structural equation modeling and Mendelian randomization decomposes maternal and fetal genetic contributions and causal links between birth weight, blood pressure and glycemic traits.
Journal ArticleDOI
Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
Rebecca C Richmond,Andrew J Simpkin,G. Woodward,Tom R. Gaunt,Oliver Lyttleton,Wendy L. McArdle,Susan M. Ring,Andrew D A C Smith,Nicholas J. Timpson,Kate Tilling,George Davey Smith,Caroline L Relton +11 more
TL;DR: Investigation of associations between prenatal exposure to maternal smoking and offspring DNA methylation at multiple time points in approximately 800 mother–offspring pairs found that the major contribution to altered methylation was attributed to a critical window of in utero exposure.