R
Regina Kunz
Researcher at University Hospital of Basel
Publications - 148
Citations - 52456
Regina Kunz is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Evidence-based medicine & Health care. The author has an hindex of 50, co-authored 135 publications receiving 41480 citations. Previous affiliations of Regina Kunz include McMaster University & University of Basel.
Papers
More filters
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Journal ArticleDOI
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
Gordon H. Guyatt,Andrew D Oxman,Elie A. Akl,Regina Kunz,Gunn Elisabeth Vist,Jan Brozek,Susan L Norris,Yngve Falck-Ytter,Paul Glasziou,Hans deBeer,Roman Jaeschke,David Rind,Joerg J Meerpohl,Philipp Dahm,Holger J. Schünemann +14 more
TL;DR: The GRADE process begins with asking an explicit question, including specification of all important outcomes, and provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
Journal ArticleDOI
GRADE guidelines: 3. Rating the quality of evidence
Howard Balshem,Mark Helfand,Mark Helfand,Holger J. Schünemann,Andrew D Oxman,Regina Kunz,Jan Brozek,Gunn Elisabeth Vist,Yngve Falck-Ytter,Joerg J Meerpohl,Susan L Norris,Gordon H. Guyatt +11 more
TL;DR: The approach of GRADE to rating quality of evidence specifies four categories-high, moderate, low, and very low-that are applied to a body of evidence, not to individual studies.
Journal ArticleDOI
What is “quality of evidence” and why is it important to clinicians?
Gordon H. Guyatt,Andrew D Oxman,Regina Kunz,Gunn Elisabeth Vist,Yngve Falck-Ytter,Holger J. Schünemann +5 more
TL;DR: Guideline developers use a bewildering variety of systems to rate the quality of the evidence underlying their recommendations as mentioned in this paper, some are facile, some confused, and others sophisticated but complex.
Journal ArticleDOI
GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Jan Brozek,Pablo Alonso-Coello,Victor M. Montori,Elie A. Akl,Ben Djulbegovic,Yngve Falck-Ytter,Susan L Norris,John W Williams,David C. Atkins,Joerg J Meerpohl,Holger J. Schünemann +14 more
TL;DR: In the GRADE approach, randomized trials start as high-quality evidence and observational studies as low- quality evidence, but both can be rated down if most of the relevant evidence comes from studies that suffer from a high risk of bias.