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Reinhard Engels

Researcher at Broad Institute

Publications -  13
Citations -  4307

Reinhard Engels is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 11, co-authored 13 publications receiving 4037 citations. Previous affiliations of Reinhard Engels include Massachusetts Institute of Technology & Stanford University.

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The genome sequence of the filamentous fungus Neurospora crassa

James E. Galagan, +77 more
- 24 Apr 2003 - 
TL;DR: A high-quality draft sequence of the N. crassa genome is reported, suggesting that RIP has had a profound impact on genome evolution, greatly slowing the creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related genes.
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The Genome of M. Acetivorans Reveals Extensive Metabolic and Physiological Diversity

James E. Galagan, +76 more
- 01 Apr 2002 - 
TL;DR: The complete genome sequence of an acetate-utilizing methanogen, Methanosarcina acetivorans C2A, is reported, which indicates the likelihood of undiscovered natural energy sources for methanogenesis, whereas the presence of single-subunit carbon monoxide dehydrogenases raises the possibility of nonmethanogenic growth.
Journal ArticleDOI

Dynamics of Pseudomonas aeruginosa genome evolution.

TL;DR: The complete sequence and comparative analysis of the genomes of two representative P. aeruginosa strains isolated from cystic fibrosis patients whose genetic disorder predisposes them to infections by this pathogen suggest that niche adaptation is a major evolutionary force influencing the composition of bacterial genomes.
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Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication

TL;DR: The order and genomic arrangement of the duplicated gene pairs and their common phylogenetic origin provide evidence for an ancestral whole-genome duplication (WGD) event that resulted in the expansion of multiple gene families related to cell growth and signal transduction, as well as secreted aspartic protease and subtilase protein families, which are known fungal virulence factors.