Showing papers by "Renata Cifkova published in 2010"
TL;DR: The current joint position is that the initiation of beta blockers in patients who will undergo non-cardiac surgery should not be considered routine, but should be considered carefully by each patient's treating physician on a case-by-case basis.
Abstract: Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery.
693 citations
TL;DR: The striking improvement in CV risk factors documented between 1985 and 2007/8 most likely contributed to the decrease in CV mortality in the Czech Republic.
136 citations
TL;DR: The reduction in population blood pressure and improved hypertension control may have contributed substantially to the decrease in cardiovascular disease mortality in the Czech Republic.
Abstract: ObjectivesTo assess longitudinal trends in cardiovascular mortality and population mean blood pressure, prevalence, awareness, treatment, and control of hypertension in a representative Czech population sample from 1985 to 2007/2008.MethodsSource data on mortality rates were provided by the Czech St
78 citations
TL;DR: Genetically determined disorder of nitric oxide metabolism was associated with increased stiffness of peripheral, muscular-type arteries in generally healthy, untreated subjects, but only in the interaction with current smoking.
Abstract: Summary Nitric oxide belongs to the most important factors influencing structural and functional properties of vessel wall. Both genetic and environmental factors may influence its metabolism. The aim of this study was to explore whether two common polymorphisms of endothelial nitric synthase (eNOS) may, jointly with smoking, influence the stiffness of large arteries, quantified as pulse wave velocity (PWV). One hundred ninety four subjects free of manifest atherosclerotic disease or chronic pharmacotherapy were selected from population-based
18 citations
14 citations
Journal Article•
TL;DR: This association of apoprotein E gene with acute coronary syndrome is strongly modified by the presence/absence of traditional cardiovascular factors of atherosclerosis in a high-risk Czech population.
Abstract: The apoprotein E gene ranks among the most discussed candidate genes for cardiovascular disease. We studied whether the association between apoprotein E gene polymorphism and manifestation of acute coronary syndrome is modulated by the presence/absence of traditional cardiovascular risk factors. The population under study were 1066 pa- tients (men under 65 years) admitted between 2006- 2009 to five coronary care units in Prague (GENetic DEtermination of Myocardial Infarction in Prague) and the control population (1066 age-matched men selected from the Czech population sample). The fre- quency of disadvantage genotype E4 + was signifi- cantly higher (P < 0.01) in acute coronary syndrome patients (22.38 %) than in controls (16.76 %). When the acute coronary syndrome group was step by step limited to non-smokers, non-diabetics and normo- tensive individuals, the odds ratio displayed a gradu- al increase from 1.35 (for the entire group) through 1.48 (non-smokers), 1.53 (non-smokers+non-diabet- ics) to 1.71 (non-smokers+non-diabetics+normoten- sives). The effect of the apoprotein E gene on the individual risk of acute coronary syndrome is non- homogenous within the patient groups. This associa- tion of apoprotein E gene with acute coronary syn- drome is strongly modified by the presence/absence of traditional cardiovascular factors of atherosclero- sis in a high-risk Czech population.
10 citations
TL;DR: Drinking of small amounts of alcohol was associated with decreased serum leptin concentration, with a possible benefit in terms of cardiovascular risk, in patients with chronic manifest coronary artery or cerebrovascular disease.
Abstract: An inverse association between serum leptin concentration and reported alcohol intake in patients with manifest vascular disease
3 citations
TL;DR: Agreement within Europe abo ut antihypertensive treatment and education – results from the European Society of Hypertension questionnaire.
Abstract: Agreement within Europe abo ut antihypertensive treatment and education – results from the European Society of Hypertension questionnaire Michael H. Olsen, Jean-Michel Mallion, Karl-Heinz Rahn, Serap Erdine, Margus Viigimaa, Stéphane Laurent, Enrico Agabiti-Rosei, Giuseppe Mancia, Roland E. Schmieder, Renata Cifkova, Anna Dominiczak, Sverre E. Kjeldsen, Josep Redon, Alberto Zanchetti, Peter Nilsson, Krzysztof Narkiewicz, on behalf of the ESH Council
3 citations
TL;DR: Several studies have shown that blood pressure can be lowered by the use of drugs that are not traditional antihypertensive drugs, which might be of clinical importance when many risk patients are treated by combination drug therapy in order to prevent cardiovascular disease.
Abstract: Several studies have shown that blood pressure can be lowered by the use of drugs that are not traditional antihypertensive drugs. This might be of clinical importance when many risk patients are treated by combination drug therapy in order to prevent cardiovascular disease by way of improving the cardiovascular risk factor profile.
2 citations
1 citations
Journal Article•
TL;DR: Adresy do korespondencji: Professor Giuseppe Mancia, Clinica Medica, University of Milan-Bicocca, San Gerardo Hospital, Via Pergolesi 33, 20052 Monza, Milan, Włochy.