scispace - formally typeset
R

René Breuer

Researcher at Heidelberg University

Publications -  47
Citations -  10204

René Breuer is an academic researcher from Heidelberg University. The author has contributed to research in topics: Genome-wide association study & Bipolar disorder. The author has an hindex of 32, co-authored 47 publications receiving 9427 citations. Previous affiliations of René Breuer include University of Mannheim & University of Göttingen.

Papers
More filters
Journal ArticleDOI

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

S. Hong Lee, +405 more
- 01 Sep 2013 - 
TL;DR: Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
Journal ArticleDOI

Common variants conferring risk of schizophrenia

Hreinn Stefansson, +94 more
- 06 Aug 2009 - 
TL;DR: Findings implicating the MHC region are consistent with an immune component to schizophrenia risk, whereas the association with NRGN and TCF4 points to perturbation of pathways involved in brain development, memory and cognition.
Journal ArticleDOI

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Pamela Sklar, +192 more
- 01 Oct 2011 - 
TL;DR: An analysis of all 11,974 bipolar disorder cases and 51,792 controls confirmed genome-wide significant evidence of association for CACNA1C and identified a new intronic variant in ODZ4, and a pathway comprised of subunits of calcium channels enriched in bipolar disorder association intervals was identified.
Journal ArticleDOI

A mega-analysis of genome-wide association studies for major depressive disorder

Stephan Ripke, +115 more
- 01 Apr 2013 - 
TL;DR: This article conducted a genome-wide association studies (GWAS) mega-analysis for major depressive disorder (MDD) using more than 1.2 million autosomal and X chromosome single-nucleotide polymorphisms (SNPs) in 18,759 independent and unrelated subjects of recent European ancestry.
Journal ArticleDOI

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Colm O'Dushlaine, +404 more
- 19 Jan 2015 - 
TL;DR: It is indicated that risk variants for psychiatric disorders aggregate in particular biological pathways and that these pathways are frequently shared between disorders.