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Rene J. Duquesnoy

Researcher at University of Pittsburgh

Publications -  153
Citations -  6045

Rene J. Duquesnoy is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Human leukocyte antigen & Epitope. The author has an hindex of 46, co-authored 152 publications receiving 5641 citations. Previous affiliations of Rene J. Duquesnoy include National Institutes of Health.

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Obliterative bronchiolitis after lung and heart-lung transplantation: An analysis of risk factors and management

TL;DR: Recipients with obliterative bronchiolitis detected in the preclinical stage were significantly more likely to be in remission than recipients who had clinical disease at the time of diagnosis and results indicate that acute rejection is the most significant risk factor for development of obliteration and that obliteration responds to treatment with augmented immunosuppression when it is detected early by surveillance transbronchial biopsy.
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Clonal dominance among T-lymphocyte infiltrates in arthritis.

TL;DR: It is suggested that a limited number of activated T-cell clones predominate at the site of tissue injury in rheumatoid synovial membranes as well as in other types of destructive inflammatory joint disease.
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HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. I. Description of the algorithm.

TL;DR: An algorithm for identifying acceptable HLA antigens for highly alloimmunized patients without the need for extensive serum screening is described, suitable especially for allosensitized patients in need of a compatible transplant or platelet transfusion.
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A structurally based approach to determine HLA compatibility at the humoral immune level.

TL;DR: The eplet version of HLAMatchmaker represents therefore a more complete repertoire of structurally defined HLA epitopes and provides a more detailed assessment of HLA compatibility.
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The acceptable mismatch program as a fast tool for highly sensitized patients awaiting a cadaveric kidney transplantation: short waiting time and excellent graft outcome.

TL;DR: This report advocates selection of crossmatch negative donors on the basis of the Acceptable Mismatch Program, as the first and best option for highly sensitized patients to undergo transplantations.