R
Renu Ohlyan
Publications - 6
Citations - 49
Renu Ohlyan is an academic researcher. The author has contributed to research in topics: Quantitative structure–activity relationship & Piper. The author has an hindex of 3, co-authored 6 publications receiving 42 citations.
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Introduction, phytochemistry, traditional uses and biological activity of genus Piper: a review
TL;DR: Piper, the pepper plants or pepper vines are an economically and ecologically important genus in the family Piperaceae, which contains about 1,000-2,000 species of shrubs, herbs, and lianas, many of which are keystone species in their native habitat.
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Pharmacophore modeling and 3D QSAR analysis of isothiazolidinedione derivatives as PTP1B inhibitors
TL;DR: The article describes the development of a robust pharmacophore model and investigation of structure activity relationship analysis of 56 isothiazolidinedione derivatives reported as PTP1B inhibitors, and suggests that hydrophobic aromatic character is crucial for the PTP 1B inhibitory activity at the R-15 site.
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In vitro screening of dry fruit extracts of Piper attenuatum for antioxidant and anticancer activity
TL;DR: None of the extract showed anticancer activity when compared with the standard (mitomycin C) indicating that P. attenuatum is deprived of antiproliferative or cytotoxic components.
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Synthesis and in vitro cholesteryl ester transfer protein inhibitory activity of novel esters of 2, 10-dichloro-12H-dibenzo [d,g] 1,3-dioxocin-6-carboxylic acid
TL;DR: Novel ester derivatives of 2, 10-dichloro-12H-dibenzo [d,g] 1,3 dioxocin-6-carboxylic acid were synthesized and evaluated for their in vitro human cholesteryl ester transfer protein (CETP) inhibition.
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Synthesis and in-vitro antiproliferative activity of 2, 3-aryl substituted 1, 3-benzoxazin-4-one derivatives
TL;DR: This class of compounds showed some initial promising activity which can be further expanded by synthesizing and testing more analogs of this kind against MCF-7 cell lines which may give good leads to proceed.