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Ric M. Procyshyn
Researcher at University of British Columbia
Publications - 164
Citations - 3972
Ric M. Procyshyn is an academic researcher from University of British Columbia. The author has contributed to research in topics: Clozapine & Antipsychotic. The author has an hindex of 31, co-authored 152 publications receiving 3439 citations. Previous affiliations of Ric M. Procyshyn include Provincial Health Services Authority & Riverview Hospital.
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Journal ArticleDOI
Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings.
William J. Panenka,Ric M. Procyshyn,Tania Lecomte,G. William MacEwan,Sean W. Flynn,William G. Honer,Alasdair M. Barr +6 more
TL;DR: A review of the evidence that chronic MA use is associated with substantial neurotoxicity and cognitive impairment and key findings in the literature spanning from molecular through to clinical effects are summarized.
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Clozapine alone versus clozapine and risperidone with refractory schizophrenia.
William G. Honer,Allen E. Thornton,Eric Y.H. Chen,Raymond C.K. Chan,Jessica O. Y. Wong,Andrea Bergmann,Peter Falkai,Edith Pomarol-Clotet,Peter J. McKenna,Emmanuel Stip,Richard Williams,G. William MacEwan,Kishor M. Wasan,Ric M. Procyshyn +13 more
TL;DR: The addition of risperidone to clozapine did not improve symptoms in patients with severe schizophrenia, and there was no statistically significant difference in symptomatic benefit between augmentation with ris peridone and placebo.
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Antipsychotic polypharmacy: a survey of discharge prescriptions from a tertiary care psychiatric institution.
TL;DR: Although antipsychotic polypharmacy persists today, as it has over the past 30 years, evidence-based data to support this controversial treatment strategy is lacking and clinicians are relying on their clinical experience, and perhaps intuition, to design antipsychotics polyphARMacy treatment protocols.
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Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system.
TL;DR: The direct and indirect effects of antipsychotic drugs on the cardiovascular system and their possible mechanisms of action are discussed in this review, where both preclinical and clinical findings are integrated.
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Persistent antipsychotic polypharmacy and excessive dosing in the community psychiatric treatment setting: a review of medication profiles in 435 Canadian outpatients.
Ric M. Procyshyn,William G. Honer,Tony K.Y. Wu,Rebecca W. Y. Ko,Sean A. McIsaac,Allan H. Young,Joy L. Johnson,Alasdair M. Barr +7 more
TL;DR: Using a diagnostically heterogeneous outpatient population, this study is the first to report that persistent antipsychotic polypharmacy is associated with excessive dosing, in and of itself as well as compared to antipsychotics monotherapy.