Author
Ricardo R. Gonzalez
Other affiliations: University of Miami, NewYork–Presbyterian Hospital, Baylor College of Medicine ...read more
Bio: Ricardo R. Gonzalez is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Lower urinary tract symptoms & Overactive bladder. The author has an hindex of 15, co-authored 52 publications receiving 1066 citations. Previous affiliations of Ricardo R. Gonzalez include University of Miami & NewYork–Presbyterian Hospital.
Papers published on a yearly basis
Papers
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TL;DR: In this pilot study, the combination of alfuzosin 10 mg OD and sildenafil 25 mg OD is safe and more effective than monotherapy with either agent to improve both voiding and sexual dysfunction in men with LUTS suggestive of BPH.
235 citations
TL;DR: Photoselective laser vaporization prostatectomy is a suitable treatment option in men being treated with anticoagulants, who are at high risk for clinically significant bleeding.
Abstract: Background and Purpose: Photoselective laser vaporization prostatectomy (PVP) with a high-power KTP laser is a hemostatic procedure for men with symptomatic benign prostatic hyperplasia (BPH). This study demonstrates the feasibility of PVP in men who are receiving anticoagulants. Patients and Methods: Men treated with PVP for symptomatic BPH between July 2002 and September 2003 who were receiving anticoagulants (N = 24) were reviewed retrospectively. Their mean age was 75 years, and the mean prostate volume was 82 cc (range 34-164 cc). Nine men (38%) were in retention, eight (33%) had had a myocardial infarction, seven (29%) had had a cerebrovascular accident, and seven had peripheral vascular disease. Of these men, 8 were on warfarin, 2 on clopidogrel, and 14 on aspirin. Men on warfarin discontinued the drug 2 days prior to surgery and restarted it the day after. The other two drugs were not discontinued. The PVP was performed with an 80 W KTP side-firing laser (Laserscope Greenlight PV) through a 23F co...
171 citations
TL;DR: The technique can be combined with reduction clitoroplasty for the surgical management of girls with masculinized external genitalia and can be accomplished with total urogenital sinus mobilization through the perineal approach.
63 citations
TL;DR: The actual costs of photoselective laser vaporization prostatectomy at affiliated hospitals are lower than those of transurethral prostate resection, and it is likely that most patients who undergo Laser vaporization are treated on an outpatient basis compared to those who undergo resection.
62 citations
TL;DR: Inflammatory models of cystitis result in increased levels of TNF-alpha, SP and NGF production in the bladder, paralleling the hypothesized neuro-inflammatory etiology of IC.
57 citations
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TL;DR: This document is designed to be used in conjunction with the associated treatment algorithm, and all patients should be informed of all treatment modalities that are not contraindicated, regardless of invasiveness or irreversibility, as potential first‐line treatments.
419 citations
TL;DR: It is proposed that, apart from low coronary risk situations, patients on antiplatelet drugs should continue their treatment throughout surgery, except when bleeding might occur in a closed space, and a therapeutic bridge with shorter-acting anti platelet drugs may be considered.
Abstract: Recent clinical data show that the risk of coronary thrombosis after antiplatelet drugs withdrawal is much higher than that of surgical bleeding if they are continued. In secondary prevention, aspirin is a lifelong therapy and should never be stopped. Clopidogrel is regarded as mandatory until the coronary stents are fully endothelialized, which takes 3 months for bare metal stents, but up to 1 yr for drug-eluting stents. Therefore, interruption of antiplatelet therapy 10 days before surgery should be revised. After reviewing the data on the use of antiplatelet drugs in cardiology and in surgery, we propose an algorithm for the management of patients, based on the risk of myocardial ischaemia and death compared with that of bleeding, for different types of surgery. Even if large prospective studies with a high degree of evidence are still lacking on different antiplatelet regimens during non-cardiac surgery, we propose that, apart from low coronary risk situations, patients on antiplatelet drugs should continue their treatment throughout surgery, except when bleeding might occur in a closed space. A therapeutic bridge with shorter-acting antiplatelet drugs may be considered.
304 citations
TL;DR: It is suggested that PDE5-Is can significantly improve LUTS and erectile function in men with BPH and seem to be a promising treatment option for patients with LUTs secondary to BPH with or without ED.
290 citations
TL;DR: Identifying the patients with IC who have mast cell proliferation and activation will enable us to address this aspect of disease pathophysiology in these individuals with targeted pharmacotherapy to inhibit mast cell activation and mediator release.
288 citations