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Ricardo Silva

Other affiliations: University of Almería
Bio: Ricardo Silva is an academic researcher from Universidade Católica de Pelotas. The author has contributed to research in topics: Parabolic trough & Population. The author has an hindex of 18, co-authored 20 publications receiving 1230 citations. Previous affiliations of Ricardo Silva include University of Almería.

Papers
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Journal ArticleDOI
TL;DR: Os achados sugerem that baixas condicoes socioeconomicas de vida da puerpera e a nao aceitacao da gravidez sao elementos-chave no desenvolvimento da depressao pos-parto no analise multivariada.
Abstract: OBJETIVO: Avaliar a prevalencia e os fatores associados a depressao pos-parto. METODOS: O estudo foi realizado na cidade de Pelotas, entre outubro e novembro de 2000. As maes (n=410) foram entrevistadas no hospital, utilizando dois questionarios sobre informacoes obstetricas e psicossociais. Posteriormente, as puerperas foram visitadas em casa, entre 30 a 45 dias depois do parto, quando foi aplicada a Escala de Hamilton com o objetivo de medir e caracterizar a presenca de sintomas depressivos. O teste do qui-quadrado foi utilizado na comparacao entre proporcoes e a regressao logistica nao condicional, na analise multivariada. Os dados foram analisados hierarquicamente: no primeiro nivel as variaveis socioeconomicas, no segundo, as variaveis demograficas, no terceiro, estavam as variaveis obstetricas e no ultimo nivel, as variaveis psicossociais. RESULTADOS: A prevalencia de depressao pos-parto encontrada foi de 19,1%. As variaveis renda familiar (OR=5,24; IC 95%: 2,00-13,69), preferencia pelo sexo da crianca (meninos: OR=3,49; IC 95%: 1,76-6,93) e pensar em interromper a gestacao (OR=2,52; IC 95%: 1,33-4,76), apresentaram associacao com a ocorrencia de depressao. CONCLUSOES: Os achados sugerem que baixas condicoes socioeconomicas de vida da puerpera e a nao aceitacao da gravidez sao elementos-chave no desenvolvimento da depressao pos-parto.

175 citations

Journal ArticleDOI
TL;DR: A critical point of view on the main MLT shows their potential ability as a valuable tool in drug design and shows that MLT have significant advantages.
Abstract: The interest in the application of machine learning techniques (MLT) as drug design tools is growing in the last decades. The reason for this is related to the fact that the drug design is very complex and requires the use of hybrid techniques. A brief review of some MLT such as self-organizing maps, multilayer perceptron, bayesian neural networks, counter-propagation neural network and support vector machines is described in this paper. A comparison between the performance of the described methods and some classical statistical methods (such as partial least squares and multiple linear regression) shows that MLT have significant advantages. Nowadays, the number of studies in medicinal chemistry that employ these techniques has considerably increased, in particular the use of support vector machines. The state of the art and the future trends of MLT applications encompass the use of these techniques to construct more reliable QSAR models. The models obtained from MLT can be used in virtual screening studies as well as filters to develop/discovery new chemicals. An important challenge in the drug design field is the prediction of pharmacokinetic and toxicity properties, which can avoid failures in the clinical phases. Therefore, this review provides a critical point of view on the main MLT and shows their potential ability as a valuable tool in drug design.

138 citations

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TL;DR: It is indicated that increased meal frequency may have a beneficial effect on a reduced BMI and physical activity and breakfast skipping may be candidate targets for prevention programmes aimed at reducing overweight/obese among adolescents.
Abstract: Objective: The purpose of this study was to assess the associations and impact of increased meal frequency, physical activity and ‘skipping’ breakfast on obesity levels in a sample of urban adolescents, aged 13–17 years old, from Porto, Portugal.Methods: Overweight and obesity were defined according to age- and sex-specific BMI cut-points. Daily meal frequency was assessed by questionnaire. Self-reported physical activity was recalled.Results: The proportion of overweight/obese girls (p ≤ 0.05) and boys (p ≤ 0.001) that consumed fewer than three meals was significantly higher than those reported from normal-weight counterparts. While no statistically significant differences were reported in girls, obese boys skipped breakfast significantly more (13% vs 5.6%; p ≤ 0.05) than normal-weight counterparts did. Normal-weight boys but not girls were significantly more active (p ≤ 0.01) than obese peers. An additional meal in boys (OR: 2.75; p ≤ 0.05) and girls (OR: 1.97; p ≤ 0.05) reduced the risk of being overwe...

134 citations

Journal ArticleDOI
TL;DR: The findings indicate that maternal age, parity, primary caregiver status and duration of post-partum depression are associated with the language development of the child.
Abstract: Background Language is one of the most important acquisitions made during childhood. Before verbal language, a child develops a range of skills and behaviours that allow the child to acquire all communication skills. Factors such as environmental factors, socio-economic status and interaction with parents can affect the acquisition of vocabulary in children. Post-partum depression can negatively affect the first interactions with the child and, consequently, the emotional, social and cognitive development of the child. Objective To analyse the effect of the duration of the mother’s depression on the language development of children at 12 months old. Methods This was a longitudinal study. The participants of this study were mothers who had received prenatal care from the Brazilian National System of Public Health in Pelotas city, State of Rio Grande do Sul, Brazil. The mothers were interviewed at two different time points: from 30 to 90 days after delivery and at 12 months after delivery; the children were also evaluated at this later time point. To diagnose maternal depression, we used the Mini International Neuropsychiatric Interview, and to assess child development, we used the language scale of the Bayley Scales of Infant Development III. Results We followed 296 dyads. Maternal depression at both time points (post partum and at 12 months) was significantly associated with the language development of infants at 12 months of age. This impact was accentuated when related to the duration of the disorder. Older women and women with more than two children were more likely to have children with poorer language development, while women who were the primary caregiver had children with higher scores on the language test. Conclusion The findings indicate that maternal age, parity, primary caregiver status and duration of post-partum depression are associated with the language development of the child.

128 citations

Journal ArticleDOI
TL;DR: Youth with a history of crack cocaine use had a higher prevalence of psychiatric conditions such as post-traumatic stress disorder, as well as an increased risk of tobacco, alcohol, cannabis, cocaine, amphetamine and inhalant use and dependence.

84 citations


Cited by
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TL;DR: Evidence for associations between parental disorders and offspring outcomes from fetal development to adolescence in high-income, middle- income, and low-income countries is summarized and the need for early identification of those parents at high risk and for more early interventions and prevention research is underlined.

1,427 citations

Journal ArticleDOI
TL;DR: The debate is attempted to shift the debate from questions about whether poverty is associated with CMD in LMIC, to questions about which particular dimensions of poverty carry the strongest (or weakest) association.

992 citations

Journal ArticleDOI
TL;DR: This review is intended to summarise findings from the existing literature, identify important knowledge gaps, and set the research agenda for creating new generalisable knowledge pertinent to increasing the authors' understanding of the prevalence, determinants, and infant and childhood health outcomes associated with perinatal depression.

626 citations

Journal ArticleDOI
TL;DR: The current prevalence of postpartum depression is much higher than that previously reported, and similar risk factors are documented.

532 citations

Journal ArticleDOI
TL;DR: The results suggest that postpartum depression creates an environment that is not conducive to the personal development of mothers or the optimal development of a child, and it seems important to detect and treat depression during the postnatal period as early as possible to avoid harmful consequences.
Abstract: Introduction:The postpartum period represents the time of risk for the emergence of maternal postpartum depression. There are no systematic reviews of the overall maternal outcomes of maternal post...

506 citations