R
Richard A. Flavell
Researcher at Yale University
Publications - 1389
Citations - 223064
Richard A. Flavell is an academic researcher from Yale University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 231, co-authored 1328 publications receiving 205119 citations. Previous affiliations of Richard A. Flavell include National Institute for Medical Research & University of Michigan.
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Journal ArticleDOI
The complete nucleotide sequence of the I-E alpha d immune response gene.
J J Hyldig-Nielsen,L. Schenning,U Hammerling,E Widmark,E Heldin,P. Lind,B Servenius,T Lund,Richard A. Flavell,J S Lee,J Trowsdale,P H Schreier,F Zablitzky,Dan Larhammar,Per A. Peterson,Lars Rask +15 more
TL;DR: The absence of I-E antigen in H-2 mice is due to lack of E alpha chain synthesis, and it is shown here that this defect is caused by a deletion in the 5' end of the I-e alpha b gene.
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Lymph Node Germinal Centers Form in the Absence of Follicular Dendritic Cell Networks
TL;DR: It is reported that lymphotoxin β–deficient mice form GC cell clusters in the gross anatomical location expected of GCs, despite the complete absence of follicular dendritic cell networks.
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Site-directed mutagenesis: Generation of an extracistronic mutation in bacteriophage Qβ RNA
TL;DR: The general approach to directed mutagenesis outlined above should allow the introduction of mutations into the 5′ and 3′-terminal regions of Qβ RNA as well as into the intercistronic sequences.
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The role of NOD-like Receptors in shaping adaptive immunity.
TL;DR: In this review, many of the recent findings in the NLR field are highlighted with a particular focus on NLR influence of adaptive immune responses.
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The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis
Claire R. Weston,Anthony Wong,J. Perry Hall,Mary E.P. Goad,Richard A. Flavell,Roger J. Davis +5 more
TL;DR: It is concluded that JNK is necessary for epithelial morphogenesis and is an essential regulator of signal transduction by the EGF receptor in the epidermis.