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Richard D. Klausner

Researcher at National Institutes of Health

Publications -  285
Citations -  58844

Richard D. Klausner is an academic researcher from National Institutes of Health. The author has contributed to research in topics: T-cell receptor & Golgi apparatus. The author has an hindex of 131, co-authored 284 publications receiving 57652 citations. Previous affiliations of Richard D. Klausner include Stowers Institute for Medical Research.

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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Robert L. Strausberg, +81 more
TL;DR: The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene.
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Brefeldin A: insights into the control of membrane traffic and organelle structure.

TL;DR: The relationship between the control of membrane traffic and the maintenance of organelle structure has been investigated with the use of a remarkable drug, brefeldin A (BFA), and some speculative models concerning the mechanism and regulation ofmembrane traffic within the central vacuolar system are proposed.
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Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER.

TL;DR: It is suggested that BFA disrupts a dynamic membrane-recycling pathway between the ER and cis/medial Golgi, effectively blocking membrane transport out of but not back to the ER.