R
Richard Durbin
Researcher at University of Cambridge
Publications - 337
Citations - 247542
Richard Durbin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Population. The author has an hindex of 125, co-authored 319 publications receiving 207192 citations. Previous affiliations of Richard Durbin include Wellcome Trust Sanger Institute & University of Manchester.
Papers
More filters
Journal ArticleDOI
The DNA sequence and comparative analysis of human chromosome 20.
Panos Deloukas,M Earthrowl,Darren Grafham,Marc Rubenfield,Lisa French,Charles A. Steward,Sarah Sims,Matthew Jones,S. Searle,Carol Scott,Kerstin Howe,Sarah E. Hunt,T D Andrews,James G. R. Gilbert,David Swarbreck,Jennifer L. Ashurst,A Taylor,J Battles,Christine P. Bird,R Ainscough,J P Almeida,R I S Ashwell,K D Ambrose,A K Babbage,C L Bagguley,J Bailey,Ruby Banerjee,K Bates,Helen Beasley,S Bray-Allen,A J Brown,J Y Brown,D C Burford,W Burrill,John Burton,Patrick Cahill,D Camire,Nigel P. Carter,J C Chapman,S Y Clark,G Clarke,C M Clee,S. M. Clegg,N Corby,Alan Coulson,Pawandeep Dhami,I Dutta,Matthew Dunn,L M Faulkner,Adam Frankish,J Frankland,P Garner,J Garnett,Susan M. Gribble,C Griffiths,Russell J. Grocock,Erik Gustafson,S Hammond,Joanna Harley,E. Hart,Paul Heath,T P Ho,B Hopkins,J Horne,Philip Howden,Elizabeth J. Huckle,C Hynds,Chris Johnson,David W. Johnson,A Kana,M. Kay,A M Kimberley,J K Kershaw,M Kokkinaki,Gavin K. Laird,S Lawlor,H M Lee,Daniel Leongamornlert,G Laird,Christine Lloyd,D. M. Lloyd,Jane E. Loveland,J Lovell,Stuart McLaren,Kirsten McLay,Amanda McMurray,M Mashreghi-Mohammadi,Lucy Matthews,Sarah Milne,T Nickerson,M Nguyen,E K Overton-Larty,Sophie Palmer,A. V. Pearce,A I Peck,Sarah Pelan,Benjamin Phillimore,K M Porter,Catherine M. Rice,A Rogosin,Mark T. Ross,Theologia Sarafidou,Harminder Sehra,Ratna Shownkeen,C. D. Skuce,Michelle Smith,L Standring,N Sycamore,J Tester,A Thorpe,W Torcasso,Alan Tracey,A Tromans,J Tsolas,Melanie M. Wall,J Walsh,H Wang,Keith Weinstock,Anthony P. West,David Willey,S. Whitehead,Laurens G. Wilming,Paul Wray,L Young,Yuan Chen,Ruth C. Lovering,Nicholas K. Moschonas,Reiner Siebert,Kim Fechtel,David Bentley,Richard Durbin,Tim Hubbard,Lynn Doucette-Stamm,Stephan Beck,Douglas Smith,Jane Rogers +135 more
TL;DR: Comparative analysis of the sequence of chromosome 20 to whole-genome shotgun-sequence data of two other vertebrates provides an independent measure of the efficiency of gene annotation, and indicates that this analysis may account for more than 95% of all coding exons and almost all genes.
Journal ArticleDOI
A survey of expressed genes in Caenorhabditis elegans.
Robert H. Waterston,Charles E. Martin,M. Craxton,C. Huynh,Alan Coulson,LaDeana W. Hillier,Richard Durbin,Philip Green,Ratna Shownkeen,Nicolette D. Halloran,Mark M. Metzstein,T. Hawkins,Richard K. Wilson,Mary Berks,Zijin Du,K. Thomas,Jean Thierry-Mieg,John Sulston +17 more
TL;DR: The result is the identification of about 1,200 of the estimated 15,000 genes of C. elegans, providing a more accurate estimate of the total number of genes in the organism than has hitherto been available.
Journal ArticleDOI
InterPro: An integrated documentation resource for protein families, domains and functional sites
Nicola Mulder,Rolf Apweiler,Teresa K. Attwood,Amos Marc Bairoch,Alex Bateman,David Binns,Margaret Biswas,Paul Bradley,Peer Bork,Phillip Bucher,Richard R. Copley,Emmanuel Courcelle,Richard Durbin,Laurent Falquet,Wolfgang Fleischmann,Jérôme Gouzy,Sam Griffith-Jones,Daniel H. Haft,Henning Hermjakob,Nicolas Hulo,Daniel Kahn,Alexander Kanapin,Maria Krestyaninova,Rodrigo Lopez,Ivica Letunic,Sandra Orchard,Marco Pagni,David Peyruc,Chris P. Ponting,Florence Servant,Christian J. A. Sigrist +30 more
TL;DR: InterPro was developed as an integrated documentation resource for protein families, domains and functional sites, to rationalise the complementary efforts of the individual protein signature database projects.
Journal ArticleDOI
WormBase: network access to the genome and biology of Caenorhabditis elegans
TL;DR: WormBase is a web-based resource for the Caenorhabditis elegans genome and its biology that builds upon the existing ACeDB database of the C.elegans genome by providing data curation services, a significantly expanded range of subject areas and a user-friendly front end.
Journal ArticleDOI
Trait variation in yeast is defined by population history.
Jonas Warringer,Jonas Warringer,Enikö Zörgö,Francisco A. Cubillos,Amin Zia,Arne B. Gjuvsland,Jared T. Simpson,Annabelle Forsmark,Richard Durbin,Stig W. Omholt,Edward J. Louis,Gianni Liti,Alan M. Moses,Anders Blomberg +13 more
TL;DR: It is shown that natural trait variation in S. cerevisiae exceeds that of its relatives, despite limited genetic variation, and follows the population history rather than the source environment, a step towards an in-depth understanding of the causal relationship between co-variation in ecology, selection pressure, natural traits, molecular mechanism, and alleles in a key model organism.