R
Richard E. Pratley
Researcher at Sanford-Burnham Institute for Medical Research
Publications - 315
Citations - 32276
Richard E. Pratley is an academic researcher from Sanford-Burnham Institute for Medical Research. The author has contributed to research in topics: Diabetes mellitus & Medicine. The author has an hindex of 75, co-authored 201 publications receiving 29665 citations. Previous affiliations of Richard E. Pratley include University of Maryland, Baltimore & National Institutes of Health.
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Journal ArticleDOI
Leptin levels in human and rodent : Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
Margherita Maffei,Jeffrey L. Halaas,Eric Ravussin,Richard E. Pratley,Gwo-Hwa Lee,Gwo-Hwa Lee,Yan Zhang,Yan Zhang,Hong Fei,S. Kim,R. Lallone,S. Ranganathan,Philip A. Kern,Philip A. Kern,Jeffrey M. Friedman,Jeffrey M. Friedman +15 more
TL;DR: Weight loss due to food restriction was associated with a decrease in plasma leptin in samples from mice and obese humans, suggesting differences in its secretion rate from fat.
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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia.
Christian Weyer,Tohru Funahashi,Sachiyo Tanaka,Kikuko Hotta,Yuji Matsuzawa,Richard E. Pratley,P. Antonio Tataranni +6 more
TL;DR: It is confirmed that obesity and type 2 diabetes are associated with low plasma adiponectin concentrations in different ethnic groups and indicate that the degree of hypoadiponectinemia is more closely related to thedegree of insulin resistance and hyperinsulinemia than to the level of adiposity and glucose intolerance.
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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus.
TL;DR: Defects in insulin secretion and insulin action occur early in the pathogenesis of diabetes, and intervention to prevent diabetes should target both abnormalities.
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Impaired fasting glucose and impaired glucose tolerance: implications for care.
David M. Nathan,Mayer B. Davidson,Ralph A. DeFronzo,Robert J. Heine,Robert R. Henry,Richard E. Pratley,Bernard Zinman +6 more
TL;DR: With the development of diabetes, there is a large increase in risk for CVD, as well as for long-term complications affecting the eyes, kidneys, and nervous system, and the risk of a CVD event is modestly increased.
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Diabetes in Older Adults
M. Sue Kirkman,Vanessa J. Briscoe,Nathaniel G. Clark,Hermes Florez,Linda B. Haas,Jeffrey B. Halter,Elbert S. Huang,Mary T. Korytkowski,Medha Munshi,Peggy Soule Odegard,Richard E. Pratley,Carrie S. Swift +11 more
TL;DR: The American Diabetes Association (ADA) convened a Consensus Development Conference on Diabetes and Older Adults (defined as those aged ≥ 65 years) in February 2012 as discussed by the authors, where a series of scientific presentations by experts in the field were independently developed.