R
Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.
Tanya M. Teslovich,Christian Fuchsberger,Vasily Ramensky,Pranav Yajnik,Daniel C. Koboldt,David E. Larson,Qunyuan Zhang,Ling Lin,Ryan P. Welch,Li Ding,Michael D. McLellan,Michele O'Laughlin,Catrina Fronick,Lucinda Fulton,Vincent Magrini,Amy J. Swift,Paul Elliott,Marjo-Riitta Järvelin,Marika Kaakinen,Mark I. McCarthy,Leena Peltonen,Leena Peltonen,Anneli Pouta,Lori L. Bonnycastle,Francis S. Collins,Narisu Narisu,Heather M. Stringham,Jaakko Tuomilehto,Samuli Ripatti,Robert S. Fulton,Chiara Sabatti,Richard K. Wilson,Michael Boehnke,Nelson B. Freimer +33 more
TL;DR: The results highlight the value of large, well-phenotyped samples for rare-variant association analysis, and the challenge of evaluating the phenotypic impact of such variants.
Journal ArticleDOI
Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses.
Shridhar Bale,Geraldine Goebrecht,Armando Stano,Richard K. Wilson,Takayuki Ota,Karen Tran,Jidnyasa Ingale,Michael B. Zwick,Richard T. Wyatt +8 more
TL;DR: First-generation nickel-based liposomes captured HIV-1 Env glycoprotein trimers via a noncovalent linkage with improved efficacy over soluble glycop protein in activating germinal center B cells and eliciting tier-2 autologous neutralizing antibodies.
Journal ArticleDOI
Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate
Anna J. Jasinska,Anna J. Jasinska,Ivette Zelaya,Christine B. Peterson,Rita M. Cantor,Rita M. Cantor,Oi Wa Choi,Joseph DeYoung,Eleazar Eskin,Lynn A. Fairbanks,Scott C. Fears,Allison E. Furterer,Yu S. Huang,Yu S. Huang,Vasily Ramensky,Vasily Ramensky,Christopher A. Schmitt,Christopher A. Schmitt,Hannes Svardal,Matthew J. Jorgensen,Jay R. Kaplan,Diego Villar,Bronwen Aken,Paul Flicek,Rishi Nag,Emily S. W. Wong,John Blangero,Thomas D. Dyer,Marina Bogomolov,Yoav Benjamini,George M. Weinstock,Ken Dewar,Chiara Sabatti,Richard K. Wilson,Richard K. Wilson,David J. Jentsch,David J. Jentsch,Wesley C. Warren,Giovanni Coppola,Giovanni Coppola,Roger P. Woods,Nelson B. Freimer,Nelson B. Freimer +42 more
TL;DR: By analyzing multitissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, a transcriptome resource and the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate model are generated.
Journal Article
A framework for human microbiome research
Barbara A. Methé,Karen E. Nelson,Mihai Pop,Heather Huot Creasy,Michelle G. Giglio,Curtis Huttenhower,Dirk Gevers,Joseph F. Petrosino,Sahar Abubucker,Jonathan H. Badger,Asif T. Chinwalla,Ashlee M. Earl,Michael Fitzgerald,Robert S. Fulton,Kymberlie Hallsworth-Pepin,Elizabeth A. Lobos,Ramana Madupu,Vincent Magrini,John Martin,Makedonka Mitreva,Donna M. Muzny,Erica Sodergren,James Versalovic,Aye Wollam,Kim C. Worley,Jennifer R. Wortman,Sarah Young,Qiandong Zeng,Kjersti Aagaard,Olukemi O. Abolude,Emma Allen-Vercoe,Eric J. Alm,Lucia Alvarado,Gary L. Andersen,Scott Anderson,Elizabeth L. Appelbaum,Harindra Arachchi,Gary C. Armitage,Cesar Arze,Tulin Ayvaz,Carl C. Baker,Lisa Begg,Tsegahiwot Belachew,Veena Bhonagiri,Monika Bihan,Martin J. Blaser,Toby Bloom,Vivien Bonazzi,Paul Brooks,Gregory A. Buck,Christian J. Buhay,Dana A. Busam,Joseph L. Campbell,Shane Canon,Brandi L. Cantarel,Patrick S. G. Chain,I-Min A. Chen,Lei Chen,Shaila Chhibba,Ken Chu,Dawn Ciulla,Jose C. Clemente,Sandra W. Clifton,Sean Conlan,Jonathan Crabtree,Mary A. Cutting,Noam J. Davidovics,Catherine C. Davis,Todd Z. DeSantis,Carolyn Deal,Kimberley D. Delehaunty,Floyd E. Dewhirst,Elena Deych,Yan Ding,David J. Dooling,Shannon Dugan,W. Michael Dunne,A. Scott Durkin,Robert C. Edgar,Rachel L. Erlich,Candace N. Farmer,Ruth M. Farrell,Karoline Faust,Michael Feldgarden,Victor Felix,Sheila A. Fisher,Anthony A. Fodor,Larry J. Forney,Leslie Foster,Valentina Di Francesco,Jonathan Friedman,Dennis C. Friedrich,Catrina Fronick,Lucinda Fulton,Hongyu Gao,Nathalia Garcia,Georgia Giannoukos,Christina Giblin,Maria Y. Giovanni,Jonathan M. Goldberg,Johannes B. Goll,Antonio Gonzalez,Allison D. Griggs,Sharvari Gujja,Brian J. Haas,Holli A. Hamilton,Emily L. Harris,Theresa A. Hepburn,Brandi Herter,Diane E. Hoffmann,Michael Holder,Clinton Howarth,Katherine H. Huang,Susan M. Huse,Jacques Izard,Janet K. Jansson,Huaiyang Jiang,Craig T. Jordan,Vandita Joshi,James A. Katancik,Wendy A. Keitel,Scott T. Kelley,Cristyn Kells,Susan Kinder-Haake,Nicholas B. King,Rob Knight,Dan Knights,Heidi H. Kong,Omry Koren,Sergey Koren,Karthik Kota,Christie Kovar,Nikos C. Kyrpides,Patricio S. La Rosa,Sandra L. Lee,Katherine P. Lemon,Niall J. Lennon,Cecil M. Lewis,Lora Lewis,Ruth E. Ley,Kelvin Li,Konstantinos Liolios,Bo Liu,Yue Liu,Chien-Chi Lo,Catherine A. Lozupone,R. Dwayne Lunsford,Tessa Madden,Anup Mahurkar,Peter J. Mannon,Elaine R. Mardis,Victor M. Markowitz,Konstantinos Mavrommatis,Jamison McCorrison,Daniel McDonald,Jean E. McEwen,Amy L. McGuire,Pamela McInnes,Teena Mehta,Kathie A. Mihindukulasuriya,Jason R. Miller,Patrick Minx,Irene Newsham,Chad Nusbaum,Michelle O'Laughlin,Joshua Orvis,Ioanna Pagani,Krishna Palaniappan,Shital M. Patel,Matthew D. Pearson,Jane Peterson,Mircea Podar,Craig Pohl,Katherine S. Pollard,Margaret Priest,Lita M. Proctor,Xiang Qin,Jeroen Raes,Jacques Ravel,Jeffrey G. Reid,Mina Rho,Rosamond Rhodes,Kevin Riehle,Maria C. Rivera,Beltran Rodriguez-Mueller,Yu-Hui Rogers,Matthew C. Ross,Carsten Russ,Ravi Sanka,Pamela Sankar,J. Fah Sathirapongsasuti,Jeffery A. Schloss,Patrick D. Schloss,Thomas M. Schmidt,Matthew B. Scholz,Lynn M. Schriml,Alyxandria M. Schubert,Nicola Segata,Julia A. Segre,William D. Shannon,Richard R. Sharp,Thomas J. Sharpton,Narmada Shenoy,Nihar U. Sheth,Gina A. Simone,Indresh Singh,Christopher Smillie,Jack D. Sobel,Daniel D. Sommer,Paul Spicer,Granger G. Sutton,Sean M. Sykes,Diana Tabbaa,Mathangi Thiagarajan,Chad Tomlinson,Manolito Torralba,Todd J. Treangen,Rebecca Truty,Tatiana A. Vishnivetskaya,Jason Walker,Lu Wang,Zhengyuan Wang,Doyle V. Ward,Wesley C. Warren,Mark A. Watson,Christopher Wellington,Kris A. Wetterstrand,James R. White,Katarzyna Wilczek-Boney,Yuan Qing Wu,Kristine M. Wylie,Todd Wylie,Chandri N. Yandava,Liang Ye,Yuzhen Ye,Shibu Yooseph,Bonnie P. Youmans,Lan Zhang,Yanjiao Zhou,Yiming Zhu,Laurie Zoloth,Jeremy Zucker,Bruce W. Birren,Richard A. Gibbs,Sarah K. Highlander,George M. Weinstock,Richard K. Wilson,Owen White +247 more
TL;DR: Resources from a population of 242 healthy adults sampled at 15 or 18 body sites up to three times are presented, which have generated 5,177 microbial taxonomic profiles from 16S ribosomal RNA genes and over 3.5 terabases of metagenomic sequence so far.
Journal ArticleDOI
Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals
Vidushi S. Patel,Steven J. B. Cooper,Steven J. B. Cooper,Janine E. Deakin,Bob Fulton,Tina Graves,Wesley C. Warren,Richard K. Wilson,Jennifer A. Marshall Graves +8 more
TL;DR: In this article, the authors analyzed genomic data from an egg-laying monotreme mammal, the platypus (Ornithorhynchus anatinus), to explore haemoglobin evolution at the stem of the mammalian radiation.