R
Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock.
Rahul Tyagi,Anja Joachim,Baerbel Ruttkowski,Bruce A. Rosa,John Martin,Kymberlie Hallsworth-Pepin,Xu Zhang,Philip Ozersky,Richard K. Wilson,Shoba Ranganathan,Paul W. Sternberg,Robin B. Gasser,Makedonka Mitreva +12 more
TL;DR: Recent advances made in biology and animal biotechnology through the draft genome and developmental transcriptome of O. dentatum are reported in order to support biological research of this and related parasitic nematodes as well as the search for new and improved interventions.
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A genetic signature of relapse in stage II colorectal cancer derived from formalin fixed paraffin embedded tissue (FFPE) tissue using a unique disease specific colorectal array
Patrick G. Johnston,Karl Mulligan,Elaine W. Kay,Julie Black,S. Moore,U. Mc Dermott,Richard K. Wilson,D. P. Harkin +7 more
TL;DR: The first colorectal cancer disease specific microarray is developed and demonstrated its use using FFPE tissues and derived a gene signature that predicts for a high likelihood of early relapse in stage II CRC.
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Improving eukaryotic genome annotation using single molecule mRNA sequencing
Vincent Magrini,Xin Gao,Bruce A. Rosa,Sean McGrath,Xu Zhang,Kymberlie Hallsworth-Pepin,John Martin,John M. Hawdon,Richard K. Wilson,Makedonka Mitreva +9 more
TL;DR: Overall, PacBio data has supported a significant improvement in gene annotation in this genome, and is an appealing alternative or complementary technique for genome annotation to the other transcript sequencing technologies.
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Somatic SLC35A2 mosaicism correlates with clinical findings in epilepsy brain tissue.
Katherine E. Miller,Daniel C. Koboldt,Kathleen M. Schieffer,Tracy A. Bedrosian,Erin Crist,Adrienne Sheline,Kristen M. Leraas,Vincent Magrini,Huachun Zhong,Patrick J. Brennan,Jocelyn M Bush,James Fitch,Natalie Bir,Anthony R. Miller,Catherine E. Cottrell,Jeffrey R. Leonard,Jonathan Pindrik,Jerome Rusin,Summit H. Shah,Peter White,Richard K. Wilson,Elaine R. Mardis,Christopher R. Pierson,Adam P. Ostendorf +23 more
TL;DR: The findings support the importance of tissue-based sequencing and highlight a correlation in a 3-year-old male patient with West syndrome and intractable tonic seizures between SLC35A2 variant allele fractions and the severity of epileptogenic phenotypes in different brain tissues obtained from a grid-based resection of clinically defined epilepsy regions.
Journal ArticleDOI
Representation of cloned genomic sequences in two sequencing vectors: correlation of DNA sequence and subclone distribution
Stephanie L. Chissoe,Marco A. Marra,LaDeana W. Hillier,Ryan R. Brinkman,Richard K. Wilson,Robert H. Waterston +5 more
TL;DR: It is suggested that complementary use of M13 and pUC subclones would provide the most comprehensive subclone coverage of a given genomic sequence.