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Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Analysis of somatic retrotransposition in human cancers
Eunjung Lee,Eunjung Lee,Rebecca C. Iskow,Lixing Yang,Omer Gokcumen,Psalm Haseley,Psalm Haseley,Lovelace J. Luquette,Jens G. Lohr,Jens G. Lohr,Chris Harris,Li Ding,Richard K. Wilson,David A. Wheeler,Richard A. Gibbs,Raju Kucherlapati,Raju Kucherlapati,Charles Lee,Peter V. Kharchenko,Peter J. Park,Peter J. Park +20 more
TL;DR: This data indicates that the epigenetic and regulatory disruptions commonly observed in cancers may allow for TE activation, and a few examples have been reported in lung and colon cancer previously.
Journal ArticleDOI
Author Correction: Elephant shark genome provides unique insights into gnathostome evolution.
Byrappa Venkatesh,Byrappa Venkatesh,Alison P. Lee,Vydianathan Ravi,Ashish K. Maurya,Michelle M. Lian,Jeremy B. Swann,Yuko Ohta,Martin F. Flajnik,Yoichi Sutoh,Masanori Kasahara,Shawn Hoon,Vamshidhar Gangu,Scott William Roy,Manuel Irimia,Vladimir Korzh,Igor Kondrychyn,Zhi Wei Lim,Boon-Hui Tay,Sumanty Tohari,Kiat Whye Kong,Shufen Ho,Belen Lorente-Galdos,Belen Lorente-Galdos,Javier Quilez,Javier Quilez,Tomas Marques-Bonet,Tomas Marques-Bonet,Brian J. Raney,Philip W. Ingham,Alice Tay,LaDeana W. Hillier,Patrick Minx,Thomas Boehm,Richard K. Wilson,Sydney Brenner,Wesley C. Warren +36 more
TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Journal ArticleDOI
Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes
John S. Welch,David E. Larson,Li Ding,Michael D. McLellan,Tamara Lamprecht,Cyriac Kandoth,Jacqueline E. Payton,Jack Baty,Chris Harris,Cheryl F. Lichti,Robert S. Fulton,David J. Dooling,Daniel C. Koboldt,Heather Schmidt,Qunyuan Zhang,John R. Osborne,Ling Lin,Michelle O'Laughlin,Joshua F. McMichael,Kim D. Delehaunty,Sean McGrath,Lucinda Fulton,Vincent Magrini,Tammi L. Vickery,Todd Wylie,Jason Walker,Peter Westervelt,Michael H. Tomasson,Mark A. Watson,Sharon Heath,William D. Shannon,Rakesh Nagarajan,Daniel C. Link,Timothy A. Graubert,John F. DiPersio,Elaine R. Mardis,Richard K. Wilson,Timothy J. Ley +37 more
TL;DR: To characterize the genomic events associated with distinct subtypes of AML, whole genome sequencing was used to compare 24 tumor/normal sample pairs from patients with normal karyotype M1-AML and t(15;17)-positive M3-AMl to identify a new leukemic pathway and several important themes emerged.
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PacBio Fusion and Long Isoform Pipeline (PB_FLIP) for Cancer Transcriptome-based Resolution of Isoform Complexity.
Anthony R. Miller,Saranga Wijeratne,Sean McGrath,Kathleen M. Schieffer,Katherine E. Miller,Kristy Lee,Mariam Thomas Mathew,Stephanie LaHaye,James Fitch,Benjamin J. Kelly,Peter White,Elaine R. Mardis,Richard K. Wilson,Catherine E. Cottrell,Vincent Magrini +14 more
TL;DR: In this article , the authors describe the utility of Iso-seq and PB_FLIP analysis in improving deconvolution of complex structural variants and isoform detection within an institutional pediatric and adolescent/young adult translational cancer research cohort.
Journal ArticleDOI
Hypomorphic alleles pose challenges in rare disease genomic variant interpretation.
Daniel K. Nolan,Daniel K. Nolan,Bimal Chaudhari,Bimal Chaudhari,Samuel J Franklin,Saranga Wijeratne,Ruthann Pfau,Ruthann Pfau,Theresa Mihalic Mosher,Theresa Mihalic Mosher,Erin Crist,Kim L. McBride,Kim L. McBride,Peter White,Peter White,Richard K. Wilson,Richard K. Wilson,Scott E. Hickey,Scott E. Hickey,Daniel C. Koboldt,Daniel C. Koboldt +20 more
TL;DR: In this article, Sashimi plot visualization of aligned RNA sequencing data from proband liver tissue at ATP7B exons 14-13-12 and exon 13 (dashed box) would remove a transmembrane domain and disrupt the first phosphorylation domain.