R
Richard L. Weiss
Researcher at University of California, Los Angeles
Publications - 38
Citations - 3048
Richard L. Weiss is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Neurospora crassa & Neurospora. The author has an hindex of 17, co-authored 38 publications receiving 2888 citations. Previous affiliations of Richard L. Weiss include University of Pennsylvania.
Papers
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Journal ArticleDOI
A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors.
Hildur V. Colot,Gyungsoon Park,Gloria E. Turner,Carol S. Ringelberg,Christopher M. Crew,Liubov Litvinkova,Richard L. Weiss,Katherine A. Borkovich,Jay C. Dunlap +8 more
TL;DR: This study describes a method for rapidly creating knockout mutants in which it makes use of yeast recombinational cloning, Neurospora mutant strains deficient in nonhomologous end-joining DNA repair, custom-written software tools, and robotics.
Journal ArticleDOI
Increased baseline occupancy of D2 receptors by dopamine in schizophrenia.
Anissa Abi-Dargham,Janine Rodenhiser,David Printz,Yolanda Zea-Ponce,Roberto Gil,Lawrence S. Kegeles,Richard L. Weiss,Thomas B. Cooper,J. John Mann,Ronald L. Van Heertum,Jack M. Gorman,Marc Laruelle +11 more
TL;DR: Elevated synaptic dopamine was predictive of good treatment response of positive symptoms to antipsychotic drugs and increased stimulation of D(2) receptors by dopamine in schizophrenia, consistent with increased phasic activity of dopaminergic neurons.
Book ChapterDOI
Enabling a community to dissect an organism: overview of the Neurospora functional genomics project.
Jay C. Dunlap,Katherine A. Borkovich,Matthew R. Henn,Gloria E. Turner,Matthew S. Sachs,N. Louise Glass,Kevin McCluskey,Michael Plamann,James E. Galagan,Bruce W. Birren,Richard L. Weiss,Jeffrey P. Townsend,Jennifer J. Loros,Mary Anne Nelson,Randy Lambreghts,Hildur V. Colot,Gyungsoon Park,Patrick D. Collopy,Carol S. Ringelberg,Christopher M. Crew,Liubov Litvinkova,David DeCaprio,Heather M. Hood,Susan Curilla,Mi Shi,Matthew Crawford,Michael Koerhsen,Phil Montgomery,Lisa Larson,Matthew D. Pearson,Takao Kasuga,Chaoguang Tian,Meray Baştürkmen,Lorena Altamirano,Junhuan Xu +34 more
TL;DR: CDNA libraries generated in Project 4 document the overall complexity of expressed sequences in Neurospora, including alternative splicing alternative promoters and antisense transcripts, and drive the assembly of an SNP map presently populated by nearly 300 markers that will greatly accelerate the positional cloning of genes.
Journal ArticleDOI
Legislative History of American Immigration Policy, 1798-1965.
Journal ArticleDOI
The relationship between enzyme activity, cell geometry, and fitness in Saccharomyces cerevisiae.
TL;DR: The results indicate that the basic biochemical parameters of the cell are primarily determined by cell geometry rather than ploidy level, and the evolution of diploidy as the predominant phase of the life cycle of higher plants and animals is discussed.