Richard Longnecker

TL;DR: By DNA transfection into human B cells, it is shown that protection from apoptosis is conferred through expression of a single EBV latent protein, the latent membrane protein LMP 1, and it is demonstrated that L MP 1 mediates this effect by up-regulating expression of the cellular oncogene bcl-2.

TL;DR: LMP2A expression results in the bypass of normal B lymphocyte developmental checkpoints allowing immunoglobulin-negative cells to colonize peripheral lymphoid organs, indicating that LMP2a possesses a constitutive signaling activity in nontransformed cells.

TL;DR: It is reported here that temperature-sensitive mutants defective in genes CDC42 and CDC43, like cdc24 mutants, fail to bud but continue growth at restrictive temperature, and thus arrest as large unbudded cells, supporting the hypothesis that the events associated with budding and those of the nuclear cycle represent two independent pathways within the cell cycle.

TL;DR: The purpose of this review is to summarize recent findings on the entry of alpha- and gammaherpesviruses and on structure-function studies of their entry receptors and viral ligands.

TL;DR: Results suggest that Btk maintains increased intracellular calcium levels by controlling a Tg‐sensitive, IP3‐gated calcium store(s) that regulates store‐operated calcium entry.