R
Richard W. Kim
Researcher at Children's Hospital Los Angeles
Publications - 59
Citations - 2651
Richard W. Kim is an academic researcher from Children's Hospital Los Angeles. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 45 publications receiving 2334 citations. Previous affiliations of Richard W. Kim include College of Osteopathic Medicine of the Pacific & Yale University.
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Journal ArticleDOI
Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Pediatric Cardiac Surgery
Chirag R. Parikh,Prasad Devarajan,Michael Zappitelli,Kyaw Sint,Kyaw Sint,Heather Thiessen-Philbrook,Simon Li,Richard W. Kim,Jay L. Koyner,Steven G. Coca,Steven G. Coca,Charles L. Edelstein,Michael G. Shlipak,Amit X. Garg,Catherine D. Krawczeski +14 more
TL;DR: Elevated urine IL-18 and urine NGAL levels associated with longer hospital stay, longer intensive care unit stay, and duration of mechanical ventilation, but not plasma NGAL, associate with subsequent AKI and poor outcomes among children undergoing cardiac surgery.
Journal ArticleDOI
Interferon-gamma elicits arteriosclerosis in the absence of leukocytes.
George Tellides,Denis A. Tereb,Nancy C. Kirkiles-Smith,Richard W. Kim,Jean H. Wilson,Jeffrey S. Schechner,Marc I. Lorber,Jordan S. Pober +7 more
TL;DR: The authors showed that IFN-gamma can induce arteriosclerotic changes in the absence of detectable immunocytes by acting on VSMCs to potentiate growth-factor-induced mitogenesis.
Journal ArticleDOI
Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery – a prospective multicenter study
Simon Li,Catherine D. Krawczeski,Michael Zappitelli,Prasad Devarajan,Heather Thiessen-Philbrook,Steven G. Coca,Richard W. Kim,Chirag R. Parikh +7 more
TL;DR: Acute kidney injury is common after pediatric cardiac surgery and is associated with prolonged mechanical ventilation and increased hospital stay and cardiopulmonary bypass time and age were independently associated with acute kidney injury risk.
Journal ArticleDOI
Cancer gene therapy using a survivin mutant adenovirus
TL;DR: PAd-T34A suppressed de novo tumor formation, inhibited by approximately 40% the growth of established tumors, and reduced intraperitoneal tumor dissemination in immunodeficient mice, suggesting that adenoviral targeting of the survivin pathway may provide a novel approach for selective cancer gene therapy.
Journal ArticleDOI
Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis
Wei Li,Wei Li,Qingle Li,Qingle Li,Yang Jiao,Lingfeng Qin,Rahmat Ali,Jing Zhou,Jacopo Ferruzzi,Richard W. Kim,Arnar Geirsson,Arnar Geirsson,Harry C. Dietz,Stefan Offermanns,Jay D. Humphrey,George Tellides,George Tellides +16 more
TL;DR: It is indicated that basal TGF-β signaling in smooth muscle promotes postnatal aortic wall homeostasis and impedes disease progression and also accelerated aneurysm growth in a murine model of Marfan syndrome.