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Rima Dada

Researcher at All India Institute of Medical Sciences

Publications -  216
Citations -  5531

Rima Dada is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Male infertility & Sperm. The author has an hindex of 38, co-authored 192 publications receiving 4392 citations. Previous affiliations of Rima Dada include AIIMS, New Delhi.

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Oxidative stress and male infertility

TL;DR: Lifestyle interventions including yoga and meditation can substantially improve the integrity of sperm DNA by reducing levels of oxidative DNA damage, regulating oxidative stress and by increasing the expression of genes responsible for DNA repair, cell-cycle control and anti-inflammatory effects.
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Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility

Ashok Agarwal, +96 more
TL;DR: Oxidation-reduction potential (ORP) can be a useful clinical biomarker for the classification of MOSI, as it takes into account the levels of both oxidants and reductants (antioxidants) and may provide a more targeted, reliable approach for administering antioxidant therapy while minimizing the risk of antioxidant overdose.
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Epigenetics and its role in male infertility

TL;DR: This review provides an overview of the epigenetic processes (histone-to-protamine exchange and epigenetic reprogramming post-fertilization), aberrant epigeneticReprogramming and its association with fertility, possible risks for ART techniques, testicular cancer and the effect of environmental factors on the epigenetics processes.
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Sperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertility

TL;DR: This review presents an updated account of tests that have better diagnostic and prognostic implications in the evaluation of sperm DNA damage, and suggests tests for sperm DNA quality are most promising.
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Evaluation of nuclear DNA damage in human spermatozoa in men opting for assisted reproduction.

TL;DR: These different techniques include single cell gel electrophoresis (COMET assay), Terminal tranferase dUTP Nick End Labelling (TUNEL), sperm chromatin structure assay (SCSA), In situ nick translation (ISNT) and acridine orange test, which are independent measure of sperm quality and assist in semen quality assessment by detecting defects in DNA integrity or Chromatin structure.