R
Rima Youil
Researcher at United States Military Academy
Publications - 6
Citations - 1793
Rima Youil is an academic researcher from United States Military Academy. The author has contributed to research in topics: Virus & Immunity. The author has an hindex of 5, co-authored 6 publications receiving 1775 citations. Previous affiliations of Rima Youil include Merck & Co..
Papers
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Journal ArticleDOI
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.
John W. Shiver,Tong-Ming Fu,Ling Chen,Danilo R. Casimiro,Mary-Ellen Davies,Robert K. Evans,Zhiqiang Zhang,Adam J. Simon,Wendy L. Trigona,Sheri Dubey,Lingyi Huang,Virginia Harris,Romnie Long,Xiaoping Liang,Larry Handt,William A. Schleif,Lan Zhu,Daniel C. Freed,Natasha Persaud,Liming Guan,Kara Punt,Aimin Tang,Minchun Chen,Keith A. Wilson,Kelly B. Collins,Gwendolyn J. Heidecker,V. Rose Fernandez,Helen C. Perry,Joseph G. Joyce,Karen M. Grimm,James C. Cook,Paul M. Keller,Denise S. Kresock,Henryk Mach,Robert D. Troutman,Lynne Isopi,Donna M. Williams,Zheng Xu,Kathryn E. Bohannon,David B. Volkin,David C. Montefiori,Ayako Miura,Georgia R. Krivulka,Michelle A. Lifton,Marcelo J. Kuroda,Jörn E. Schmitz,Norman L. Letvin,Michael J. Caulfield,Andrew J. Bett,Rima Youil,David C. Kaslow,Emilio A. Emini +51 more
TL;DR: The replication-defective adenovirus is a promising vaccine vector for development of an HIV-1 vaccine and elicited by a replication-incompetent Ad5 vector, used either alone or as a booster inoculation after priming with a DNA vector.
Journal ArticleDOI
Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
Danilo R. Casimiro,Ling Chen,Tong-Ming Fu,Robert K. Evans,Michael J. Caulfield,Mary-Ellen Davies,Aimin Tang,Minchun Chen,Lingyi Huang,Virginia Harris,Daniel C. Freed,Keith A. Wilson,Sheri Dubey,De-Min Zhu,Denise K. Nawrocki,Henryk Mach,Robert D. Troutman,Lynne Isopi,Donna M. Williams,William M. Hurni,Zheng Xu,Jeffrey G. Smith,Su Wang,Xu Liu,Liming Guan,Romnie Long,Wendy L. Trigona,Gwendolyn J. Heidecker,Helen C. Perry,Natasha Persaud,Timothy J. Toner,Qin Su,Xiaoping Liang,Rima Youil,Michael Chastain,Andrew J. Bett,David B. Volkin,Emilio A. Emini,John W. Shiver +38 more
TL;DR: Results are suggestive of an immunization strategy for humans that is centered on use of the adenovirus vector and in which existing adenavirus immunity may be overcome by combined immunization with adjuvanted DNA and adenvirus vector boosting.
Patent
Enhanced First Generation Adenovirus Vaccines Expressing Codon Optimized HIV1-Gag, Pol, Nef and Modifications
Emilio A. Emini,Rima Youil,Andrew J. Bett,Ling Chen,David C. Kaslow,John W. Shiver,Timothy J. Toner,Danilo R. Casimiro +7 more
TL;DR: In this article, first generation adenoviral vectors and associated recombinant adnovirus-based HIV vaccines which show enhanced stability and growth properties and greater cellular-mediated immunity are described within this specification.
Journal ArticleDOI
Two novel mutations of the FMO3 gene in a proband with trimethylaminuria.
B.R. Akerman,Susan M. Forrest,Lionel M.L. Chow,Rima Youil,Melanie A. Knight,Eileen P. Treacy +5 more
TL;DR: This report is the first evidence of compound heterozygosity for two rare mutations in a proband with trimethylaminuria, and suggests that other rarer alleles, also causing TMA, will be found in the same populations.
Journal ArticleDOI
Enzymatic mutation detection (EMD) of novel mutations (R565X and R1523X) in the FBN1 gene of patients with Marfan syndrome using T4 endonuclease VII.
Rima Youil,Rima Youil,Timothy J. Toner,Evelyn Bull,Anne L. Bailey,Christopher D. Earl,Harry C. Dietz,Robert A. Montgomery +7 more
TL;DR: It is proposed that the EMD method is a sensitive and rapid approach to mutation detection in large genes such as FBN1, which resulted in premature termination of translation in classic Marfan syndrome.