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Ritesh Singh

Bio: Ritesh Singh is an academic researcher from Samsung. The author has contributed to research in topics: Password & Zoom. The author has an hindex of 1, co-authored 8 publications receiving 3 citations.

Papers
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Journal ArticleDOI
Ritesh Singh1
TL;DR: The same immuno-suppresive and Immuno-modulatory properties of CQ and HCQ which render them useful as therapeutic agents in viral pneumonia and cytokine storm syndrome, are also expected to make them dangerous prophylactic agents against viral infections.
Abstract: Significant interest in application of Chloroquine (CQ) and Hydroxychloroquine (HCQ) for prophylaxis and treatment of COVID-19 has been recently reported throughout the world. In the light of this, it has become important to revisit the mechanisms of action, as well as clinical evidence for efficacy of CQ and HCQ in similar viral infections. We note that while some evidence exists for therapeutic efficacy of CQ and HCQ in mitigating morbidities associated with virus-induced inflammation and immuno-hyperactivity, abundant caution is necessary in expecting prophylactic efficacy in the light of therapeutic evidence. In particular, we intend to draw urgent attention to the fact that the same immuno-suppressive and immuno-modulatory properties of CQ and HCQ which render them useful as therapeutic agents in viral pneumonia and cytokine storm syndrome, are also expected to make them dangerous prophylactic agents against viral infections. We also intend to draw attention to some other potential concerns associated with widespread prophylactic usage of CQ and HCQ.

3 citations

Journal ArticleDOI
01 Nov 2017
TL;DR: A contemporary system based on user name, user id, password and encryption technique which can be placed in banks, protected offices to beef the security up.
Abstract: The growth of image processing in embedded system has provided the boon of enhancing the security in various sectors. This lead to the developing of various protective strategies, which will be needed by private or public sectors for cyber security purposes. So, we have developed a method which uses digital water marking and locking mechanism for the protection of any closed premises. This paper describes a contemporary system based on user name, user id, password and encryption technique which can be placed in banks, protected offices to beef the security up. The burglary can be abated substantially by using a proactive safety structure. In this proposed framework, we are using water-marking in spatial domain to encode and decode the image and PIR(Passive Infrared Sensor) sensor to detect the existence of person in any close area.
Journal ArticleDOI
TL;DR: A user-friendly tool to assist clinicians and policy makers, to determine optimal testing pool and sub-pool sizes for their specific scenarios is developed.
Abstract: Pooling together samples and testing the resulting mixture is gaining considerable interest as a potential method to markedly increase the rate of testing for SARS-CoV-2, given the resource limited conditions. Therefore, it has become important to design a user-friendly tool to assist clinicians and policy makers, to determine optimal testing pool and sub-pool sizes for their specific scenarios. We have developed such a tool (riteshsingh.github.io/poolsize). The algorithms employed are described in this paper. The code is open source for review and critique (github.com/RiteshSingh/poolsize​).
Journal ArticleDOI
TL;DR: In this paper, Ritesh Singh and Douglas Duhaime have made an open-source web simulation to study 3D distribution of galaxies in the universe out to < 200 Mpc.
Abstract: Ritesh Singh and Douglas Duhaime have made an open-source web simulation to study 3D distribution of galaxies in the universe out to < 200 Mpc – and they want you to use it.
Journal ArticleDOI
Ritesh Singh1
TL;DR: In this article, the authors analyzed 91,742 reported extragalactic distance moduli and their one sigma uncertainties for 14,560 galaxies with multiple reported distances in the NED Redshift-Independent Distances database.
Abstract: We analyze 91,742 reported extragalactic distance moduli and their one sigma uncertainties for 14,560 galaxies with multiple reported distances in the NED Redshift-Independent Distances database. For every ordered pair of distance moduli measurements 1 and 2 for each galaxy, we define $\Delta (\sigma )_{1,2}$ , a measure for how different measurement 2 is in relation to measurement 1, as a multiple of the reported one sigma uncertainty in measurement 1. For a given set of distance moduli measurements, we take a mean of all such $\Delta (\sigma )_{1,2}$ to determine the average separation between distance moduli of any galaxy in the set as a multiple of the reported uncertainty. For normally distributed measurements, the expected value of mean $\Delta (\sigma )$ is 0.79. Our results are as follows. The mean $\Delta (\sigma )$ of 1,239,062 ordered pairs of extragalactic distance moduli for 14,560 galaxies is 2.07 corresponding to a p-value of 3.85%. This indicates a possible systematic underestimation of uncertainties in extragalactic distances. We also find that the mean reported one sigma uncertainty decreased and the mean $\Delta (\sigma )$ increased from 1989 to 2018. This points to increased underestimation of uncertainties with time. For the latest period from 2014 to 2018 with 14,580 reported extragalactic distance moduli for 5,406 galaxies, the mean $\Delta (\sigma )$ of 40,462 ordered pairs is 3.00 corresponding to a p-value of 0.27%. For 14,888 extragalactic distance moduli of 2,518 galaxies measured using Type Ia Supernovae, the mean $\Delta (\sigma )$ for 124,016 ordered pairs is 2.85 corresponding to a p-value of 0.44%. These results may have some implications for our confidence in cosmological parameters and models. We conclude that more liberal estimation of uncertainties in future reported extragalactic distances should be considered. The results also give a possible way out of the Hubble-Lemaitre tension by advocating for increasing the error bars on Hubble-Lemaitre constant measured via distance ladders of standard candles and rulers.

Cited by
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Journal ArticleDOI
TL;DR: The importance of nutrition as a mitigation strategy to support immune function amid the COVID-19 pandemic is speculated, identifying food groups and key nutrients of importance that may affect the outcomes of respiratory infections.
Abstract: The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 countries. As a result, there has been considerable economic distress globally and a significant loss of life. Sadly, the vulnerable and immunocompromised in our societies seem to be more susceptible to severe COVID-19 complications. Global public health bodies and governments have ignited strategies and issued advisories on various handwashing and hygiene guidelines, social distancing strategies, and, in the most extreme cases, some countries have adopted "stay in place" or lockdown protocols to prevent COVID-19 spread. Notably, there are several significant risk factors for severe COVID-19 infection. These include the presence of poor nutritional status and pre-existing noncommunicable diseases (NCDs) such as diabetes mellitus, chronic lung diseases, cardiovascular diseases (CVD), obesity, and various other diseases that render the patient immunocompromised. These diseases are characterized by systemic inflammation, which may be a common feature of these NCDs, affecting patient outcomes against COVID-19. In this review, we discuss some of the anti-inflammatory therapies that are currently under investigation intended to dampen the cytokine storm of severe COVID-19 infections. Furthermore, nutritional status and the role of diet and lifestyle is considered, as it is known to affect patient outcomes in other severe infections and may play a role in COVID-19 infection. This review speculates the importance of nutrition as a mitigation strategy to support immune function amid the COVID-19 pandemic, identifying food groups and key nutrients of importance that may affect the outcomes of respiratory infections.

368 citations

Journal ArticleDOI
TL;DR: How the spread of SARS-CoV-2 in low- and middle-income countries might impact these efforts to control other infectious diseases is discussed, focusing in particular on the effects of co-infection and the use of antimalarial drugs used to treat malaria as therapeutic interventions for COVID-19.

41 citations

Journal ArticleDOI
14 Sep 2020
TL;DR: The study focused on exploring how individual lifestyles in the rural areas have been affected in the face of COVID19 pandemic by identifying the vulnerabilities in social, political and economic systems which can amplify the impacts of the pandemic.
Abstract: Public health professionals working in rural communities are aware of the health disparities which result from lack of physicians, limited services, and income during the pandemic. Also they are aware that some populations are more vulnerable than others. People in the rural areas are experiencing problems on their physical, social and economic life styles because the pandemic is exacerbating some inequities. Individuals especially women and children in the rural areas are facing barriers in accessing health care services due to lack of resources and availability of health care providers in the communities. With COVID-19, women are less likely to seek services, including sexual and reproductive health services. Such services may be postponed to limit exposure to COVID-19 infection. This is particularly disturbing because in addition to the women maintaining their own health, they are also responsible for taking care of the mental, emotional and physical health needs of their families as well as all domestic responsibilities. As such, women in rural settings face special challenges as a result of these significant roles they play. Therefore, the impacts of COVID-19 are exacerbated on women by virtue of their sex and the roles they play in the family. This is a qualitative study that reviewed the reports of the 36 health care professionals under the aegis of members of COVID-19 committee working in partnership with state government to control, prevent and cushion the effects of COVID-19 in the society. This study is therefore, a summary of the observations of the COVID-19 committee members made up of 10(27.8%) females and 26(72.2%) males. The study focused on exploring how individual lifestyles in the rural areas have been affected in the face of COVID19 pandemic by identifying the vulnerabilities in social, political and economic systems which can amplify the impacts of the pandemic. Findings showed that preventive measures like lockdown and social distancing rules, wearing of face mask, hand washing with soap, and environmental cleanliness were not observed. The study noted that health seeking behaviours, sexual and marital life including income, education, employment and social interactions were all negatively affected. Most hospitals were battered and health care professionals boycotted the hospitals for fear of being infected. It was found that lack of health workers in the hospitals caused a good number of individuals to engage in self-medications. Also most pregnant women delivered their babies at home and few with traditional birth attendants. Some of the women who had deliveries at home experienced complications during and after delivery. Unfortunately, the report showed that governments’ financial supports to these DOI: 10.14302/issn.2693-1176.ijgh-20-3545 INTERNATIONAL JOURNAL OF GLOBAL HEALTH

1 citations