R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Posted ContentDOI
Sequence-structure-function relationships in the microbial protein universe
Julia Koehler Leman,Paweł Szczerbiak,P. Douglas Renfrew,Vladimir Gligorijević,Daniel Berenberg,Tommi Vatanen,Bryn C. Taylor,Chris Chandler,Stefan Janssen,Nicholas Carriero,Ian M. Fisk,Ramnik J. Xavier,Rob Knight,Richard Bonneau,Tomasz Kosciolek +14 more
TL;DR: It is shown that the structural space is continuous and largely saturated, highlighting the need for shifting the focus from obtaining structures to putting them into context, to transform all branches of biology, including a shift from sequence-based to sequence-structure-function based meta-omics analyses.
Journal ArticleDOI
Comparison of lenalidomide plus dexamethasone therapy used at first relapse versus later salvage therapy in relapsed or refractory multiple myeloma patients
Edward Stadtmauer,Donna M. Weber,R. Nieszvizky,Andrew Belch,Henry Miles Prince,J F San Miguel,Thierry Facon,Zhinuan Yu,Rob Knight,M.A. Dimopoulos +9 more
TL;DR: When used at first relapse compared with salvage therapy, lenalidomide plus dexamethasone treatment resulted in significantly prolonged TTP, PFS, and OS, and an improved quality of response.
Predictive modeling of metagenomes
TL;DR: Predictive modeling of human-associated and environmental microbial communities is introduced, increasing the ability to understanding the diversity and distribution of the human microbiota, and especially the systematic changes that occur in different physiological and disease states.
Peer ReviewDOI
Author response: A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice
Timothy R. Sampson,Collin Challis,Neha Jain,Anastasiya Moiseyenko,Mark S. Ladinsky,Gauri G. Shastri,Taren Thron,Brittany D. Needham,István T. Horváth,Justine W. Debelius,Stefan Janssen,Rob Knight,Pernilla Wittung-Stafshede,Viviana Gradinaru,Matthew George Chapman,Sarkis K. Mazmanian +15 more