R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Establishing microbial composition measurement standards with reference frames
James T. Morton,Clarisse Marotz,Alex D. Washburne,Justin D. Silverman,Livia S. Zaramela,Anna Edlund,Karsten Zengler,Rob Knight +7 more
TL;DR: The notion of “reference frames” is defined, which provide deep intuition about the compositional nature of microbiome data, which allow reassessment of published relative abundance data to reveal reproducible microbial changes from standard sequencing output without the need for new assays.
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Global patterns in the biogeography of bacterial taxa
Diana R. Nemergut,Elizabeth K. Costello,Micah Hamady,Catherine A. Lozupone,Lin Jiang,Steven K. Schmidt,Noah Fierer,Alan R. Townsend,Cory C. Cleveland,Lee F. Stanish,Rob Knight +10 more
TL;DR: In this article, the authors reveal patterns in the distribution of individual bacterial taxa at multiple levels of phylogenetic resolution within and between Earth's major habitat types and show that the most cosmopolitan taxa are also the most abundant in individual assemblages.
Journal ArticleDOI
Supervised classification of human microbiota.
TL;DR: This review demonstrates that several existing supervised classifiers can be applied effectively to microbiota classification, both for selecting subsets of taxa that are highly discriminative of the type of community, and for building models that can accurately classify unlabeled data.
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Fast-Find: A novel computational approach to analyzing combinatorial motifs
TL;DR: Fast-FIND is easy to implement, takes less than a second to search the entire Drosophila genome sequence for arbitrary patterns adjacent to sites of alternative polyadenylation, and is sufficiently fast to allow sensitivity analysis on the patterns.
Journal ArticleDOI
The Human Microbiome Project: A Community Resource for the Healthy Human Microbiome
Dirk Gevers,Rob Knight,Rob Knight,Joseph F. Petrosino,Katherine H. Huang,Amy L. McGuire,Bruce W. Birren,Karen E. Nelson,Owen White,Barbara A. Methé,Curtis Huttenhower,Curtis Huttenhower +11 more
TL;DR: The NIH Human Microbiome Project (HMP) as discussed by the authors is a large-scale effort to study the human microbial community, including a brief review of human microbiome research, a history of the project, and a comprehensive overview of the consortium's recent collection of publications analyzing the human microbiome.