Rob Knight

TL;DR: It is found that antifungal function of the amphibian skin mucosome predicts the prevalence of infection with the fungal pathogen in natural populations, and is linked to survival in laboratory exposure experiments.

TL;DR: A subset of mucosal-associated gut bacteria that consistently translocated and remained viable in CrF in CD ileal surgical resections is discovered, and Clostridium innocuum is identified as a signature of this consortium with strain variation between mucosal and adipose isolates, suggesting preference for lipid-rich environments.

TL;DR: The performance of recently released state-of-the-art open-source clustering software products, namely, OTUCLUST, Swarm, SUMACLUST, and SortMeRNA, against current principal options in QIIME, hierarchical clustering methods in mothur, and USEARCH’s most recent clustering algorithm, UPARSE are evaluated.

TL;DR: It is shown that a citizen-science, self-selected cohort shipping samples through the mail at room temperature recaptures many known microbiome results from clinically collected cohorts and reveals new ones, and that the extent of microbiome change after events such as surgery can exceed differences between distinct environmental biomes.

TL;DR: Lenalidomide plus bortezomib was well tolerated and showed promising activity with durable responses in patients with relapsed and relapsed/refractory multiple myeloma, including patients previously treated with lenalidomides, bortzomib, and/or thalidomid.