R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Journal ArticleDOI
Geography and location are the primary drivers of office microbiome composition
John Chase,Jennifer Fouquier,Mahnaz Zare,Derek L. Sonderegger,Rob Knight,Scott T. Kelley,Jeffrey A. Siegel,J. Gregory Caporaso +7 more
TL;DR: A study on the impacts of geography, material type, human interaction, location in a room, seasonal variation, and indoor and microenvironmental parameters on bacterial communities in offices finds that offices have city-specific bacterial communities, such that it can accurately predict which city an office microbiome sample is derived from, but office- specific bacterial communities are less apparent.
Journal ArticleDOI
Mass spectrometry searches using MASST
Mingxun Wang,Alan K. Jarmusch,Fernando Vargas,Fernando Vargas,Alexander A. Aksenov,Julia M. Gauglitz,Kelly C. Weldon,Kelly C. Weldon,Daniel Petras,Ricardo Silva,Robert A. Quinn,Robert A. Quinn,Alexey V. Melnik,Justin J. J. van der Hooft,Justin J. J. van der Hooft,Andrés Mauricio Caraballo-Rodríguez,Louis-Félix Nothias,Christine M. Aceves,Morgan Panitchpakdi,Elizabeth Brown,Francesca Di Ottavio,Nicole Sikora,Emmanuel O. Elijah,Lara Labarta-Bajo,Emily C. Gentry,Shabnam Shalapour,Kathleen E. Kyle,Sara P. Puckett,Jeramie D. Watrous,Carolina S. Carpenter,Amina Bouslimani,Madeleine Ernst,Austin D. Swafford,Elina I. Zuniga,Marcy J. Balunas,Jonathan L. Klassen,Rohit Loomba,Rob Knight,Nuno Bandeira,Nuno Bandeira,Pieter C. Dorrestein +40 more
TL;DR: A webenabled mass spectrometry (MS) search engine, named Mass Spectrometry Search Tool (MASST), is introduced by enabling searches of all small-molecule tandem MS (MS/MS) data in public metabolomics repositories, it is proposed that MASST will unlock these resources for clinical, environmental and natural product applications.
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IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis.
Chris Callewaert,Chris Callewaert,Teruaki Nakatsuji,Rob Knight,Tomasz Kosciolek,Alison Vrbanac,Paul Kotol,Marius Ardeleanu,Thomas Hultsch,Emma Guttman-Yassky,Robert Bissonnette,Jonathan I. Silverberg,James G. Krueger,Alan Menter,Neil M.H. Graham,Gianluca Pirozzi,Jennifer D. Hamilton,Richard L. Gallo +17 more
TL;DR: Clinical improvement of AD that is mediated by interleukin-4 receptor α inhibition and the subsequent suppression of type 2 inflammation is correlated with increased microbial diversity and reduced abundance of S. aureus.
Journal ArticleDOI
Quantifying and Understanding Well-to-Well Contamination in Microbiome Research.
TL;DR: A previously undocumented form of contamination, well-to-well contamination, is described, and it is shown that this sort of contamination primarily occurs during DNA extraction rather than PCR, is highest with plate-based methods compared to single-tube extraction, and occurs at a higher frequency in low-biomass samples.
Journal ArticleDOI
The mind-body-microbial continuum.
Antonio Gonzalez,Jesse Stombaugh,Catherine A. Lozupone,Peter J. Turnbaugh,Jeffrey I. Gordon,Rob Knight +5 more
TL;DR: The human microbiome serves as the interface between the authors' genes and their history of environmental exposures; explorations of their microbiomes offer the possibility of providing new insights into their neurodevelopment and their behavioral phenotypes by affecting complex processes such as inter- and intra personal variations in cognition, personality, mood, sleep, and eating behavior.