Robert D. Barber

TL;DR: The complete genome sequence of an acetate-utilizing methanogen, Methanosarcina acetivorans C2A, is reported, which indicates the likelihood of undiscovered natural energy sources for methanogenesis, whereas the presence of single-subunit carbon monoxide dehydrogenases raises the possibility of nonmethanogenic growth.

TL;DR: The current understanding of the genome is described when data from both the Joint Genome Institute and The University of Texas-Houston Medical School are combined, suggesting that the two chromosomes are equal partners sharing responsibilities for fundamental cellular processes.

TL;DR: A PHP application, Prophage Finder, has been developed and implemented to predict prophage loci, based upon clusters of phage-related gene products encoded within DNA sequences, and results detailing several facets of these clusters are provided to facilitate rapid prediction and analysis of prophages sequences.

TL;DR: The genome sequence of the aceticlastic methanoarchaeon Methanosaeta concilii GP6, comprised of a 3,008,626-bp chromosome and an 18,019-bp episome, has been determined and exhibits considerable differences in gene content from that of MethAnosaeta thermophila.

TL;DR: Using a position-dependent weight matrix approach, prokaryotic genome sequences were screened for SmtB/ArsR DNA binding sites using data derived from intergenic sequences upstream of orthologous genes encoding these regulators.