Robert Fagard

TL;DR: In this paper, the average treatment effect in both sexes and to determine whether available data show significant differences in treatment effect between women and men was quantified by a subgroup meta-analysis of individual patient data according to sex.

TL;DR: In this paper, a meta-analysis of randomized controlled trials involving dynamic aerobic endurance training or resistance training was performed, showing that training induced significant net reductions in resting and daytime ambulatory blood pressure of, respectively, 3.0/2.6 and 3.3/3.5 mmHg.

TL;DR: In high-risk patients, the benefits from SBP lowering below 130 mmHg are driven mostly by a reduction of stroke; myocardial infarction is unaffected and cardiovascular mortality is unchanged or increased.

TL;DR: In this paper, a meta-analysis of individual participant-level data from 48 randomised trials of pharmacological blood pressure lowering medications versus placebo or other classes of blood pressure-lowering medications, or between more versus less intensive treatment regimens, was performed.

TL;DR: In the placebo group, but not the active treatment group, increased night-time systolic blood pressure variability on admission to the Syst-Eur trial was an independent risk factor for stroke during the trial.