Robert Fagard

TL;DR: The data demonstrate that the effects of Ang II on collagen secretion and production in adult rat cardiac fibroblasts in culture are AT1-receptor mediated, since they were abolished by the specific AT1/receptor antagonist, telmisartan, but not by thespecific AT2-recept antagonist, P-186.

TL;DR: The mechanism responsible for the late increase in plasma aldosterone during long-term angiotensin II suppression with captopril remains to be elucidated.

TL;DR: There appears to be little doubt that reverse dipping is associated with a worse prognosis in hypertensive patients without cardiovascular disease at baseline and with statistical adjustment for confounders and 24-h blood pressure, while mortality was lower in extreme dippers than in dippers, whereas the incidence of cardiovascular events was higher in reverse dippers.

TL;DR: The findings suggest that prenatal programming of adult blood pressure occurs at least in female twins, and suggest that particularly maternal influences, experienced by both twin members, may underlie the association between birth weight and blood pressure.

TL;DR: In this paper, the authors investigated the possible contribution of the angiotensin receptor subtypes 1 (AT1) and 2 (AT2) to changes in collagen secretion and production in rat adult cardiac fibroblasts.