Robert Fagard

TL;DR: Plasma aldosterone concentration in normal subjects was significantly and negatively related to age and to the 24-h urinary sodium excretion, and this direct radioimmunoassay using an antibody of high specificity is described, which is simpler and less time-consuming.

TL;DR: Twin analysis does not indicate that models for blood pressure regulation in various age groups should take into account the possibility of age-related changes in the expression of relevant genes, in the presence of relevant environmental agents, or in the susceptibility to the latter.

TL;DR: A favourable influence on prognosis by active treatment can be expected on the basis of the blood pressure reduction and in the absence of major electrolytes disturbances, but this benefit must be proven by observed statistical differences in terminating events between the groups.

TL;DR: In the actively treated group the fall in blood pressure in the more hypertensive patients was accompanied by a fall both in haematocrit and serum cholesterol, and in patients with less severe hypertension, active treatment was not accompanied byA fall in either hematocrit or cholesterol.

TL;DR: The increment in blood pressure with age was weaker, especially in young and middle-aged subjects (20-60 years), while the increase inBlood pressure with body mass index was also reduced, and the within-subject differences between the conventional and ambulatory blood pressure measurements increased with older age and greater bodymass index.