R
Robert J. Deans
Researcher at Osiris Therapeutics, Inc.
Publications - 116
Citations - 30793
Robert J. Deans is an academic researcher from Osiris Therapeutics, Inc.. The author has contributed to research in topics: Progenitor cell & Stem cell. The author has an hindex of 45, co-authored 116 publications receiving 28091 citations. Previous affiliations of Robert J. Deans include University of Southern California & University of Michigan.
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Journal ArticleDOI
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
Massimo Dominici,K. Le Blanc,Ingo Mueller,I. Slaper-Cortenbach,Frank C. Marini,Diane S. Krause,Robert J. Deans,Armand Keating,Darwin J. Prockop,Edwin M. Horwitz +9 more
TL;DR: The Mesenchymal and Tissue Stem Cell Committee of the International Society for Cellular Therapy proposes minimal criteria to define human MSC, believing this minimal set of standard criteria will foster a more uniform characterization of MSC and facilitate the exchange of data among investigators.
Journal ArticleDOI
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo.
Amelia Bartholomew,Cord Sturgeon,Mandy Siatskas,Karen Ferrer,Kevin R. Mcintosh,Sheila Patil,Wayne Hardy,S. Devine,David S. Ucker,Robert J. Deans,Annemarie Moseley,Ronald Hoffman +11 more
TL;DR: Baboon MSCs have been observed to alter lymphocyte reactivity to allogeneic target cells and tissues, which may prove useful in future applications of tissue regeneration and stem cell engineering.
Journal ArticleDOI
Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement
Edwin M. Horwitz,K. Le Blanc,Massimo Dominici,Ingo Mueller,I. Slaper-Cortenbach,Frank C. Marini,Robert J. Deans,Diane S. Krause,Armand Keating +8 more
TL;DR: The mesenchymal stromal cells (MSC) as mentioned in this paper have been proposed as a more scientifically correct nomenclature for the fibroblast-like cells, regardless of the tissue from which they are isolated.
POSITION PAPER Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement
Edwin M. Horwitz,K Le Blanc,Massimo Dominici,Ingo Mueller,I. Slaper-Cortenbach,Frank C. Marini,Robert J. Deans,Diane S. Krause,Armand Keating +8 more
TL;DR: It is suggested that the fibroblast-like plastic-adherent cells, regardless of the tissue from which they are isolated, be termed multipotent mesenchymal stromal cells, while the term mesenchyal stem cells is used only for cells that meet specified stem cell criteria.
Journal ArticleDOI
Mesenchymal stem cells: Biology and potential clinical uses
TL;DR: Preclinical and early clinical safety studies are paving the way for further applications of mesenchymal stem cells in the field of transplantation with respect to hematopoietic support, immunoregulation, and graft facilitation.